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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Programming Metabolically Fit TILs for Immunotherapy
SBC: LIPO-IMMUNO TECH LLC Topic: NCIABSTRACT Advances in molecular biology and genetic engineering have led to the design and use of modified T cells recognize tumors to achieve significant tumor control upon adoptive cell transfer (ACT) to patients. These T cells are either transduced with tumor antigen reactive T cell receptors (TCR), or chimeric antigen receptors (CARs). Recently, a surge in studies with neo-antigen reactive T ce ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Microfluidic Technology for Concurrent Assessment of Red Blood Cell Adhesion and Deformability
SBC: BIOCHIP LABS, INC. Topic: NHLBIPROJECT SUMMARY Deformability and non-adherence are the most intrinsic biorheological properties of red blood cells (RBCs), as they play a critical role in modulating RBC perfusion through the microvasculature. In acquired or inherited blood disorders, such as sickle cell disease (SCD), these two interrelated properties are pathologically altered. SCD is an autosomal recessive disorder associated ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Synthetic Aperture Radar(SAR) Image Generation Data Augmentation
SBC: ETEGENT TECHNOLOGIES, LTD. Topic: DTRA21B001Machine learning algorithms have demonstrated performance on par with or superior to human analysts on large datasets when sufficient training data is available. For military applications obtaining sufficient, truthed data is always a challenge. Three approaches have been used for measured data collections to support sensor exploitation programs: coordinated collections, turntable measurements ...
STTR Phase II 2023 Department of DefenseDefense Threat Reduction Agency -
A dual-acting small molecule for the treatment of type 1 diabetes
SBC: ASAKE BIOTECHNOLOGY, LLC Topic: NIDDKProject Summary: Over 1.5 million Americans suffer from type 1 diabetes (T1D), an autoimmune disorder involving insulin, a hormone that is essential for blood glucose regulation and overall energy metabolism. When first diagnosed with T1D, it is estimated that the patient’s insulin has been reduced by 70-90%. By this point, the immune system has already targeted and destroyed a vast majority of ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
SciDAP: Scientific Data Analysis Platform
SBC: DATIRIUM LLC Topic: NHGRIThe recent proliferation of next-generation sequencing (NGS) - based methods for the analysis of expression, chromatin and protein-DNA interactions has created tremendous opportunities for gaining insights into biology, health, and disease. However, analysis of the data requires computational expertise that many biologists do not possess. Hence, when dealing with genomics data, majority of biologi ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Endothelialized microfluidic assays for emerging therapies in sickle cell disease
SBC: BIOCHIP LABS, INC. Topic: NHLBITBD
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Development of SP-A Derived Peptidomimetics for the Treatment of Asthma- Phase II
SBC: RaeSedo, LLC Topic: NHLBICurrent treatments for asthma, while reducing exacerbations in a subset of patients by focusing on airway inflammation, do not eliminate them. Asthma exacerbations are a significant cause of morbidity and mortality in asthma as they can lead to airway injury, lung function decline and death. Exacerbations in more severe asthmatics are of particular concern, as health care costs and lost productivi ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Critical angle reflection imaging for label-free quantification of molecular interactions
SBC: BIOSENSING INSTRUMENT INC Topic: 400TITLE: Critical angle reflection imaging (CARi) for label-free quantification of molecular interactions SUMMARYMeasuring molecular interactions of proteins are critical for understanding protein functions and cellular processes, for discovery and validating biomarkers, and for developing and screening drugs. In particular, membrane proteins play key roles in many cellular functions and are the lar ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Affordable sialoglycans and associated reagents for expanded chemoenzymatic production
SBC: Integrated Micro-Chromatography Systems, Inc. Topic: 300Project Summary Sialoglycans are sialic acid-containing oligosaccharides that play important biological roles in human biology and pathology and are indispensable molecular probes for research related to bacterial and viral infection, cancer metastasis, immune regulation, etc. The multifaceted functions of sialoglycans in human milk are also being explored. Nevertheless, sialoglycan-related resear ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Phase II: In-field analysis of trace U and Pu by electrochemical pre-concentration
SBC: AWAREABILITY TECHNOLOGIES, LLC Topic: DTRA20B003The Defense Threat Reduction Agency (DTRA) needs a capability to collect and provide immediate presumptive analysis of radiological/nuclear samples of concern at the source of collection. Such in-field technologies should be capable of detecting and identifying trace quantities of elements and/or chemicals containing plutonium (Pu) and uranium (U), with a focus on chemicals specific to the nuclear ...
STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency