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Award Data
The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.
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Generalizing and Standardizing fMRI Tools for Differentiating Mental Illnesses and Predicting Medication-Class Response in Patients
SBC: ADVANCED BIOMEDICAL INFORMATICS GROUP, L.L.C. Topic: 102Project Summary/AbstractMood disorders, like many psychiatric conditions, have their onset in emerging adulthood and often last a lifetime. Mental illnesses have an excessively large loading of Disability Adjusted Life Years, making early intervention crucial for both individuals and society. Differentiating bipolar disorder (BD) from major depressive disorder (MDD) based on the Diagnostic and Sta ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
An Automated Patient Chart Error Detection System for Radiation Therapy
SBC: Infondrian LLC Topic: 101Project Summary/Abstract Every year, approximately 1,200 severe mistreatments happen in radiation therapy. Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $313,000 per claim settled or litigated. The current method for detecting treatment errors is by a weekly patient chart check, where each treatment record is manually reviewed on a weekly basis. Thi ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
An aptasensor to distinguish Dengue virus from Zika virus
SBC: Aptalogic, Inc. Topic: NIAIDThe diseases caused by dengue virusesDENVmosquito borne members of the family Flaviviridaehave emerged as the most important arthropod borne viral diseases of humansThe frequencygeographical distributionand severity of DENV epidemics have increased dramatically over the past decadeDENV is spread by mosquito species that also harbor Zika virusZIKVand yellow fever virusAlthough these viruses are end ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome
SBC: Oscillavent Inc Topic: NHLBIProject SummaryAbstractRespiratory failure from the acute respiratory distress syndromeARDSaccounts formillion ICU days annually in the U Splacing a significant burden on public health resourcesLung protective ventilation relies on positive end expiratory pressurePEEPto limit end expiratory derecruitmentand low tidal volumes to reduce inspiratory overdistentionWhile such ventilatory strategies hav ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Improved detection of bladder cancer recurrence using a biophysical biomarker
SBC: SynderBio Inc. Topic: 102Bladder cancer is the fifth most commonly diagnosed cancer in the United StatesThree quarters of the nearlymen and women diagnosed with bladder cancer just this year will have a less aggressive form of the disease whichafter treatmentwill require frequent visits to the urologist for invasivepainful cystoscopy procedures for the remainder of their lifetimes to determine if the cancer has returnedAn ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Precision, pulmonary disease evaluation and lung cancer detection using quantitative low-dose CT
SBC: VIDA DIAGNOSTICS, INC. Topic: 102DESCRIPTION provided by applicant Lung cancer is responsible for more cancer deaths than breast prostate and colon cancers combined Minimal improvements in the five year survival rate for lung cancer have occurred over the past thirty years Recently a mortality benefit has been demonstrated for lung cancer screening using low dose computed tomography LDCT in people with high cancer risk ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
An Automated Patient Chart Error Detection System for Radiation Therapy
SBC: Infondrian LLC Topic: 101Project Summary Abstract Every year approximately severe mistreatments happen in radiation therapy Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $ per claim settled or litigated The current method for detecting treatment errors is by a weekly patient chart check where each treatment record is manually reviewed on a weekly basis Thi ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A New Prostate Cancer Treatment to Improve Outcomes and Reduce Side-effects
SBC: PXALPHA, L.L.C. Topic: 102PROJECT SUMMARY ABSTRACT Among men prostate cancer is the most common non skin cancer and second leading cause of cancer death with over new diagnoses expected in Approximately of men will be diagnosed with prostate cancer in their lifetime Current treatment options for prostate cancer however have sub optimal incidences of side effects that have a significant impact on pa ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A brief iPad based screening measure for HIV associated neurocognitive disorders
SBC: Digital Artefacts LLC Topic: 105Despite significance advances in anti retroviral treatments HIV associated neurocognitive disorder HAND remains prevalent and can affect a broad range of everyday activities An effective brief cognitive screen that could be implemented in busy HIV clinics where clinicians have limited time to provide care for patients with complex medical psychiatric and cognitive conditions has the poten ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of Novel Small Molecule Therapies for Skeletal Muscle Atrophy
SBC: EMMYON, INC. Topic: NIADESCRIPTION (provided by applicant): Skeletal muscle atrophy is a widespread and serious medical problem. Frequent causes of skeletal muscle atrophy include orthopedic injuries, bed rest, advanced age, cancer, heart failure, COPD, diabetes, stroke, renalfailure, critical illness and spinal cord injury. Effects of skeletal muscle atrophy include weakness, reduced activity, falls, fractures, debili ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health