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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. 2-HOBA for Treatment of Pulmonary Hypertension

    SBC: MTI Biotech Incorporated            Topic: NHLBI

    PROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. An Improved Epigenetic Algorithm for Guiding Low Dose CT Lung Cancer Screening

    SBC: BEHAVIORAL DIAGNOSTICS, INC.            Topic: NCI

    SPECIFIC AIMSApproximately 90% of lung cancer results from smoking. Low Dose Computerized Tomography (LDCT) of smokers can detect lung cancer earlier allowing more effective treatment. But determining which smokers should get LDCT screening is controversial and potentially harmful. Recently, the U.S Preventive Services Task Force (USPSTF) updated their opinion on screening to recommend annual LDCT ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Booth™ by Opio™: Developing technology to expand the reach of opioid treatment programs into rural and underserved areas.

    SBC: Opio Connect, Inc.            Topic: NIDA

    The goal of this project is to develop a treatment booth with technology that allows opioid treatment programs to remotely dispense, either methadone or buprenorphine, under medical observation through telemedicine to a patient in a treatment booth. We believe that robotic automation is the ideal application to perform the same mechanical functions of the nurse at the dosing window. Specifically, ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. A Virtual Project-Based Learning Sandbox for Mimetics and Medically Inspired Classroom Engineering (MiMICRE)

    SBC: PARAMETRIC STUDIO, INC.            Topic: 500

    Project Summary/Abstract: The U.S. has more health science STEM jobs available than qualified workers to fill them and lags other OECD nations in math and science, with major achievement gaps and STEM workforce under-representation among women and students of color. Improved STEM education is needed in high school and early collegiate settings that engages, prepares, and inspires all students—an ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Image-guided dosimetry-based alpha particle therapy for neuroblastoma.

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: 105

    SIGNIFICANCE: Neuroblastoma is the most common pediatric cancer, accounting for 15% of cancer deaths, with a 5-yr survival of lt40% due to resistant metastases. Neuroblastoma tumors almost universally express the somatostatin receptor 2 (SSTR2) and high expression has been shown clinically using peptides targeting SSTR2 (PMID10706954). FDA approved SSTR2-targeted beta(β-)-emitting 177Lu-labeled L ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Live Cell Fluorescent Assays for SARS-CoV-2 protease activity and COVID-19 Drug Discovery

    SBC: MONTANA MOLECULAR LLC            Topic: NIAID

    SUMMARY STATEMENT The SARS-CoV-2 virus depends upon two proteases for replication, 3CLpro and PLpro. If one or both of these proteases can be blocked, COVID-19 infection can be effectively treated. Montana Molecular makes and sells live cell, fluorescent biosensor assays for disease research and drug discovery. In response to the COVID-19 pandemic, Montana Molecular applied its expertise and backg ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Combining receptor-targeted alpha particle therapy and immunotherapy to achieve complete responses in metastatic melanoma

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: NCI

    Revised. Metastatic melanoma is a lethal disease because low response rates (near 50%), acquired resistance, and severe adverse side effects limit long-term quality of life for these patients (5-yr. survival lt30%). Radiopharmaceutical therapies are emerging as an exciting alternative in oncology and systemic receptor- targeted alpha-particle therapy (a-RT) is emerging as particularly transformati ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Ultrasound-based diagnostic and monitoring of bladder cancer treatment with drug released from nanoparticles

    SBC: NANOMEDTRIX LLC            Topic: NCI

    Project Summary/Abstract: Transitional cell carcinoma (TCC) of the bladder is the fifth most common form of cancer in the U.S., with over 80,000 new cases expected in 2019. For early-stage carcinomas, patients receive intravesical bacillus Calmette-Guerin (BCG) immunotherapy, or transurethral resection of the bladder tumor (TURBT) with intravesical chemotherapy. Both are associated with a high rat ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation

    SBC: RESTOREAR DEVICES LLC            Topic: NIDCD

    Project Summary The goal of our project is to finalize, validate, and prepare for regulatory approvals a device and probe for delivering localized, controlled therapeutic hypothermia to the inner ear. The device safety and efficacy will be tested for residual hearing preservation in cochlear implant surgeries by comparing pre- and post-operative hearing outcomes and intra-operative electrophysiolo ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Nav1.7 Selective Inhibitors for the Treatment of Chronic Cough

    SBC: SITEONE THERAPEUTICS, INC.            Topic: NHLBI

    PROJECT SUMMARYChronic cough, or cough that persists for more than eight weeks, is a condition that is often associated with diseases such as chronic obstructive pulmonary disorder (COPD), asthma, idiopathic pulmonary fibrosis, bronchiectasis or gastroesophageal reflux disease (GERD). In other cases, the etiology is unknown, although it has been noted that the cough often first arises following a ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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