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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Solving Sepsis: Early Identification and Prompt Management Using Machine Learning

    SBC: Cohere-Med, Inc.            Topic: 300

    Abstract This fast-track STTR application proposes to enhance, validate, and scale Sepsis Watch, a deep learning sepsis detection and management system built using data from the Emergency Department (ED) Duke University Hospital (DUH). The proposal will extend and enhance Sepsis Watch to EDs, general inpatient wards, and intensive care unit (ICU) settings across multiple health systems in the Unit ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes

    SBC: VALA SCIENCES, INC.            Topic: NHLBI

    Cardiotoxicity is a leading cause of drug discovery attrition across all of preclinical and clinical drug discovery. While the FDA and the Comprehensive in vitro Proarrhythmia Assay initiative (CiPA) are focused primarily on predicting proarrhythmic effects, drug attrition due to cardiomyopathy, or primary cardiac cytotoxicity, may be even more prevalent, is typically currently only carried out vi ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Automated Mental Health Referral System

    SBC: MiResource, Inc.            Topic: 104

    This proposal addresses a significant barrier to obtaining treatment for college-ageyouth with mental disorders. Many college-age youth with impairing mental disordersremain untreated because of concerns about stigma and privacy, inconvenience and wait times, andbecause universities are often unable to service all such students. Also, of critical importance,when referral for treatment is implement ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. 2-HOBA for Treatment of Pulmonary Hypertension

    SBC: MTI Biotech Incorporated            Topic: NHLBI

    PROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. A digital tool for monitoring speech decline in ALS

    SBC: MODALITY.AI , INC            Topic: NIDCD

    PROJECT SUMMARY Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease resulting in the progressive loss of limb, trunk, and head and neck (bulbar) motor function and is the most common adult-onset motor neuron disease. The disease is characterized by significant across-patient heterogeneity in the onset region and in pattern and progression rate, making early and accurate diagno ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Endovascular ChemoFilter to Reduce Doxorubicin Toxicity during Intra-Arterial Chemotherapy

    SBC: FILTRO MEDICAL INC.            Topic: 102

    PROJECT SUMMARYDosing of chemotherapeutics is limited by systemic toxic side effects. We are developing a new class of image- guided temporarily deployable, endovascular catheter-based medical devices that selectively remove specific drugs from the blood stream to reduce systemic toxicities. The proposed ChemoFilters incorporate specialized materials that bind target drugs in situ through a variet ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Low-Energy Additive Construction for the Moon and Mars

    SBC: MASTEN SPACE SYSTEMS, INC.            Topic: T7

    The technology presented in this proposal has the capability of providing surface stabilization for landing pads, and a low-energy solution to build roads and other early components of infrastructure that are needed to kickstart a functional lunar or Martian base. The proposed innovation is a novel binder chemistry for the formation of a high-strength, heat-tolerant, regolith-binder composite mate ...

    STTR Phase II 2023 National Aeronautics and Space Administration
  8. Spectroscopic System for the Accurate Determination of [O2], [CO2], d18O-O2, d13C-CO2, and Ethylene in Plant Chambers

    SBC: NIKIRA LABS INC.            Topic: T6

    In this STTRnbsp;program, Nikira Labs Inc. and Colorado State University (CSU) will collaborate to develop an analyzer that measures oxygen (O2), carbon dioxide (CO2), oxygen isotope (d18O-O2), carbon isotope (d13C-CO2), and ethylene fluxes in plant chambers for direct quantification of photosynthesis, respiration, and plant health.nbsp;In Phase I, Nikira Labs and CSU demonstrated technical feasib ...

    STTR Phase II 2023 National Aeronautics and Space Administration
  9. Advanced Design Tools for Electrosail Propulsion Systems

    SBC: PARTICLE MATTERS, INC            Topic: T2

    The primary goal of thisnbsp;STTR Phase II project is predictive modeling ofnbsp;E-sail spacecraft thruster performancenbsp;usingnbsp;a high-fidelity computational approach. We plan to develop parallel 3D Particle-In-Cell (PIC) codesnbsp;with improved boundary conditions to simulate interactions between the solar wind plasma and E-sail, which will be validated against thrust-stand measurements of ...

    STTR Phase II 2022 National Aeronautics and Space Administration
  10. Nanomaterials Based In-Line Sensor for Ionic Silver in Spacecraft Potable Water Systems

    SBC: INNOSENSE CORPORATION            Topic: T6

    nbsp;The National Aeronautics and Space Administration (NASA) is seeking technologies for the in‚Äëline measurement of ionic silver (Ag+) in spacecraft potable water systems. Ionic silver is currently baselined as the biocide to replace iodine for microbial control with the goal of maintaining the water quality during human exploration missions. To address this need, InnoSensenbsp;LLC (ISL) is ...

    STTR Phase II 2022 National Aeronautics and Space Administration
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