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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters

    SBC: NYTRICX INC            Topic: NHLBI

    Abstract Nytricx is developing a new class of Nitric Oxide (NO)-releasing intravascular medical catheters to combat infection and thrombosis associated with indwelling vascular catheters. NO gas is a natural anti-infective and anti-thrombotic human product principally released from blood vessels and immune cells. Nytricx NO-releasing technology to the catheter surfaces via a polymer matrix, mimics ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. 2-HOBA for Treatment of Pulmonary Hypertension

    SBC: MTI Biotech Incorporated            Topic: NHLBI

    PROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Disseminable Evidence-Based Treatment for the Dental Office: Virtual Exposure Tools for Dental Fear- neVR Fear the Dentist

    SBC: VIRTUALLY BETTER INC            Topic: NIDCR

    PROJECT SUMMARY/ABSTRACTEach year over 20 million adults with moderate fear and over 14 million adults with severe fear visit the dentist. Because fear portends poor future oral health, patients with dental fear come to experience their worst fears: pain, surgical procedures, and the need for more frequent dental visits. Avoidance is the natural and reinforced response, ironically guaranteeing a r ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Imaging Bacterial Infections in Vivo: First in Man Studies

    SBC: Microbial Medical, Inc.            Topic: NIAID

    Project Summary/AbstractInfection is the major complication of virtually all medical devices. It is estimated that 2 million patients acquire a nosocomial infection in the US every year and the CDC estimates that the financial impact of these infections exceeds 5 billion dollars annually. At least half of these infections are directly associated with medical devices. Most commonly, the diagnosis o ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Small-molecule therapy for metastatic castration-resistant prostate cancer

    SBC: MetCure Therapeutics LLC            Topic: 102

    Metastatic, castration-resistant prostate cancer (mCRPC) is lethal with no cure. Although current treatments initially prolong survival, patients generally relapse and develop therapeutic resistance, which is a major obstacle in the management of prostate cancer. It is imperative to develop efficacious therapies to treat lethal mCRPC and improve the survivorship of patients. During the Phase I STT ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Microneedle Based Targeted Allergen Specific Immunotherapy for Treatment of Peanut Allergies

    SBC: MOONLIGHT THERAPEUTICS, INC.            Topic: NIAID

    Microneedle Based Targeted Allergen Specific Immunotherapy for Treatment of Peanut Allergies Food allergies affect 15 million people in the USA and 17 million in Europe. Six million children, roughly 1 in 13, in the USA have at least one food allergy; this equates to at least 1 in every classroom. Currently, there are no approved therapies for food allergies anywhere in the world. Food allergies a ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Isotopically Labeled Glycoproteins for use as Internal Standards

    SBC: GLYCOSCIENTIFIC, L.L.C.            Topic: 300

    Project Summary/Abstract The ability to accurately quantitate the glycan chains attached to glycoproteins has wide-ranging implications. Numerous studies over the past 40 years have demonstrated that abnormal glycosylation occurs in virtually all types of human cancers, and demonstrates the potential of using glycan markers in either a diagnostic or a prognostic manner. The glycosylation on recomb ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Preventing Vascular Complications in Type 1 Diabetes: Muscle Metabolic Monitoring

    SBC: Infrared Rx, Inc.            Topic: NIDDK

    Preventing Vascular Complications in Type 1 Diabetes: Muscle Metabolic Monitoring Abstract Measurements of muscle metabolism and blood flow using near infrared spectroscopy (NIRS) have progressively increased, as has the number of companies selling NIRS-based devices. This technology represents the present and future modality for non-invasively characterizing normal and abnormal muscle physiology ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. An Automated Patient Chart Error Detection System for Radiation Therapy

    SBC: Infondrian LLC            Topic: 101

    Project Summary/Abstract Every year, approximately 1,200 severe mistreatments happen in radiation therapy. Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $313,000 per claim settled or litigated. The current method for detecting treatment errors is by a weekly patient chart check, where each treatment record is manually reviewed on a weekly basis. Thi ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Novel sanitizer/disinfectants against viral infections with long-lasting effect

    SBC: CAMELLIX, LLC            Topic: NIAID

    AbstractNorovirus is the most common cause of acute gastroenteritis in the United States, associated annually with 19-21 million illnesses, 56,000-71,000 hospitalizations and 570-800 deaths (US CDC, Overview about Norovirus). Norovirus is one of the nonenveloped viruses that are resistant to alcohol sanitization. According to US CDC Guidelines for the Prevention and Control of Norovirus Gastroente ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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