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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Inhibition of methanogenesis

    SBC: BIONEBRASKA, INC.            Topic: N/A

    DESCRIPTION:(provided by applicant) The goal of this project is to develop a novel inhibitor of methane formation in ruminant animals. Currently, monensin, a relatively nonspecific antibiotic, is widely used in the livestock industry. Monensin increases agricultural productivity by decreasing methane and increasing propionate production; however, it also inhibits ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. OTOREFLECTANCE ASSESSMENT OF MIDDLE-EAR FUNCTIONING

    SBC: Sonicom, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Otoreflectance (OR) is a new class of hearing test instruments utilizing acoustic signals presented and recorded in the ear canal. OR instruments address limitations in existing screening and diagnostic instruments in such areas as: (1) detecting otitis media, (2) predicting conductive hearing loss, (3) augmenting the newborn hearing screening protocol to test ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  3. A Peptide-Based Vaccine to Nicotine

    SBC: Prommune, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The primary objective of this Phase I STTR project is to develop an effective, peptide-based nicotine vaccine for use in humans capable of inducing a robust, nicotine-specific antibody (Ab) response with little or no inflammatory side effects. This will be accomplished by a vaccine design in which a conformationally biased, response-selective agonist Of C5a ( ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. The Molecular Culture

    SBC: TRANSGENOMIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In the clinical setting, molecular microbiologic detection methods have classically focused on a single microorganism or a small group of microorganisms. Broad range molecular detection of bacteria in clinical specimens is an approach that parallels a conventional culture-based approach, may be more rapid, and offers the possibility of identifying so-called "n ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. OTOREFLECTANCE ASSESSMENT OF MIDDLE-EAR FUNCTIONING

    SBC: Sonicom, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Otoreflectance (OR) is a new class of hearing-test instruments utilizing acoustic signals presented and recorded in the ear canal. OR instruments address the following limitations in existing instruments to screen and diagnose middle-ear function: (1) detection of otitis media, (2) prediction of conductive hearing loss, (3) detection of middle-ear dysfunction i ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Response-Selective C5a Agonist for the Treatment of Asthma

    SBC: Prommune, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): An unmet need in the treatment of allergic asthma is an effective therapeutic strategy that focuses on an underlying cause of the disease rather than merely treating or managing its symptoms. At least one well- accepted underlying contributor to the pathophysiologic expression of asthma is an over-expressed and dysregulated T helper type 2 (Th2)-mediated immun ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): This project relates directly to the PHS 2011-2, Omnibus Solicitation for SBIR/STTR Grant Application page NIDCR 110: Development of instrumentation for early caries detection and comparison studies on specificity andselectivity with respect to current clinical practice. The proposed test is intended to enable dentists to differentiate between cavitated and ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Ultrafine Particles for Intranasal Delivery of Antipsychotics

    SBC: LNKCHEMSOLUTIONS            Topic: NIMH

    DESCRIPTION: The goal of the proposed project is to develop a biocompatible ultrafine particle-based vector system for the intranasal delivery of clozapine for the pharmacological therapy of treatment- resistant schizophrenic disorders and their associatedsuicidal behavior. The rationale behind the use of intranasal clozapine is grounded on the observation of clozapine's extensive first- pass ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Early Detection of Pancreatic Cancer Using Ice COLD-PCR

    SBC: TRANSGENOMIC, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): Ninety percent of all pancreatic cancers are pancreatic ductal adenocarcinoma (PDAC). PDAC diagnosis is difficult, usually occurring in the late stages of disease. Patients with these advanced tumors typically respondpoorly to therapy. Post diagnosis, median survival is 6 months and the five-year survival rate is lt 4%. Five-year survival is lt 1% for those wi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. Temperature-Tolerant COLD-PCR enables mutation-enriched targeted re-sequencing

    SBC: TRANSGENOMIC, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Cancers develop from the life-long accumulation of critical somatic mutations due to DNA-damaging agents that lead to cells transforming into tumor-forming cells. These low-level tumor-associated somatic DNA mutations can have profound implications for development of metastasis, prognosis, choice of treatment, follow-up or early cancer detection. Unless they ar ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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