Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Prognostic Blood Test to Monitor Pancreatic Cancer Treatment by MiRNA Profiling

    SBC: VAJRA INSTRUMENTS, INC.            Topic: 102

    Pancreatic ductal adenocarcinomaPDAChas ayear survival rate of less thanThe success in developing therapies for other cancers over the last two decades has not improved the dismal overall survivalOSrate for PDACIt is now becoming increasingly apparent that personalized medicine based on the genetics of a tumor will be essential for developing a treatment strategyThusthere is an urgent need to deve ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Pancreatic ductal adenocarcinomaPDACis a highly lethal form of cancerIn most patientsdetection is at an advanced stage and the outcome is poorThis project is directed towards development of a molecularly targeted ultrasound contrast agent with potential to detect early stage disease while still curableIn Phase I of this projectwe incorporated the engineered human single chain variable fragmentscFv ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of New Improved Perflutren Ultrasound Contrast Agent

    SBC: MICROVASCULAR THERAPEUTICS LLC            Topic: NHLBI

    Three ultrasound contrast agentsDefinityOptisonand Lumasonare FDA approved forechocardiography in the U SDefinity currently has overmarket shareDefinity s dominance in the marketis due to its ease of administration via IV infusion and robust ultrasound contrastDefinityhas shelflife ofyears and must be stored under refrigerated conditionsDefinity has an unpleasant side effect of back pain inaboutof ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Kinome wide Cell Based Assays

    SBC: LUCEOME BIOTECHNOLOGIES, L.L.C.            Topic: 300

    DESCRIPTION provided by applicant The human genome encodes protein kinases that catalyze the phosphorylation of client proteins Signal transduction mediated by protein impacts virtually all aspects of cellular physiology from the coordination of the cell cycle and cll division to apoptosis Not surprisingly the deregulation of kinases is implicated in many diseases including diabetes in ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Lab-To-Marketplace: Commercialization of a stretchable microelectrode array

    SBC: BMSEED LLC            Topic: 101

    Project Summary Abstract The proposed work is directed at the commercialization of BMSEEDandapos s Micro Electrode Array Stretching Stimulating und Recording EquipmentMEASSuREtechnologyMEASSuRE bridges the gap between in vitro and in vivo research by simulating the biomechanical and electrical environment of cells in the body in a controlled environment outside of the bodyThe applications for MEAS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Sustained release gel enabling one stage treatment of prosthetic joint infection

    SBC: Sonoran Biosciences, Inc.            Topic: NIAMS

    Principal Investigator Overstreet Derek J Abstract Sonoran Biosciences Inc SBIR PAR Direct Phase II Prosthetic joint infections PJIs are especially costly requiring two surgeries at a cost of approximately $ per case to treat more than hip and knee replacement infections each year The near term outlook in this area is bleak with the number of infections growing ov ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 400

    Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government