Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Wireless, implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary Abstract Neuroscience research over the last decade has been revolutionized by many technological advancementsPharmacology and optogenetics represent two distinctand sometimes complementary tools used in neuroscience research to study the central and peripheral nervous systems in the context of the BRAIN initiativeAdvanced interrogations of underlying neural circuits and biology ar ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Monochromatic 222 nm UV light: Development of a safe, cost-effective technology for the efficient reduction of bacterial and viral infection and transmission

    SBC: EDEN PARK ILLUMINATION, INC.            Topic: NIAID

    Drug resistant bacteria such as MRSAand airborne transmitted microbes such as influenza and TBpresent significant health issueswith major healthcare and economic consequencesUV light is a well established highly efficient anti microbial modalityeffective both against both bacteria and virusesHowever it is not possible to use UV sterilization in scenarios where people are present because it is both ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Developing a peptide-based oral drug to prevent kidney stones

    SBC: Oxalo Therapeutics, Inc.            Topic: 400

    Project Summary Abstract Kidney stonesKSare highly prevalentexcruciatingand associated with long term complications of chronic kidney diseaseCKDand end stage renal diseaseESRDThey account forM ER visits and andgt $B of medical costs annually and have a striking recurrence rate ofinyears and up toinyearsreflecting the inadequacies of current interventionsof KS are composed of calcium oxalate and sm ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. 4-(Aminomethyl) benzamides as novel anti-Ebola agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    EbolaEBOVand MarburgMARVviruses belong to the Filoviridae family and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction after an incubation period ofdaysDue to safety concernsthese viruses are designated as biosafety levelagentsCurrentlythere is no effective vaccine or therapeutic treatment for filoviral infections in humansAfrica has recentlysuffered a lethal EBOV e ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Application of PPODA-QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    PROJECT SUMMARY ABSTRACTA cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brainOften going unnoticed and untreatedan aneurysm can cause a sudden and catastrophic hemorrhage or strokeApproximatelyof patients die from an aneurysm rupture even before receiving medical attention andof patients die despite medical treatmentPatients that survive typ ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Albumin Nanoparticles Incorporating Piceatannol (PANPs) for ALI/ARDS therapy

    SBC: Nano Biotherapeutics, Inc.            Topic: NHLBI

    Sepsis induced ALI ARDS is a devastating syndrome of acute respiratory failure in critically ill patients that accounts for among the highest admission rates in ICU and mortalityDuring STTR Phasewe at Cell Biologics Incdemonstrated that piceatannola naturally occurring anti inflammatory that selectively inhibits Syk tyrosine kinasewhen entrapped in innm albumin nanoparticlesPANPswas therapeuticall ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Newborn Infant Vision Test

    SBC: Precision Vision, Inc.            Topic: N

    Project Summary! This STTR Phase II project continues the development of the Newborn Acuity Cardstm and the Newborn Contrast Cardstm Together these Newborn Cards form a new clinical test of visual acuity and contrast sensi tivity for use on newborn full term and preterm infants The stimuli are square wave gratings which the examiner presents to the infant in a fixation and following protocol ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government