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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. N/A

    SBC: Insect Biotechnology, Inc.            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  2. N/A

    SBC: Seashell Technology LLC            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  3. NOVEL THERAPEUTIC APPROACH TO PSORIASIS

    SBC: BETHESDA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): Psoriasis is a common, inflammatory disease of the skin characterized by hyper-proliferation of keratinocytes. A variety of antipsoriatic therapies are available, however, due to problems with side effects and variability in clinical response, intense clinical and commercial interest remains in the development of new treatments. Thiaz ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  4. AIRWAY PERFUSION ASSISTED LIQUID VENTILATOR

    SBC: MALLARD MEDICAL CO., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We have developed and patented (U.S. Pat No. 5,706,830) a new type of closed circuit perfluorocarbon (PFC) liquid ventilator with enhanced capabilities for gas exchange and exudates clearance from the lungs. This system has potential application to rescue of patients in acute respiratory failure and treatment of cystic fibrosis. ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Compact Tunable Mid-IR/UV Laser/Ion source for IR MALDI

    SBC: OPOTEK, INC.            Topic: N/A

    The goal of this Phase II STTR cooperative research program between OPOTEK and Emory University is to continue development of a small and inexpensive infrared laser based on optical parametric oscillator (OPO) technology and to develop a target system specifically designed for liquid matrix IR-MALDI. This package of IR laser and ion source is designed for high-end MALDI mass spectrometers, and wil ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Simulations to Detect Impaired Drivers

    SBC: Systems Technology, Inc.            Topic: N/A

    DESCRIPTION: Millions of individuals in the U.S. are affected by dementing disorders. Detecting driving impairments in these individuals in a safe, reliable and cost-efficient manner remains a formidable challenge. The overarching goal of Phase II is to complete development of novel, low-cost PC-based computer driving simulations that are valid for the ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. DRIVING SIMULATOR FOR PERSONS WITH IMPAIRED COGNITION

    SBC: Systems Technology, Inc.            Topic: N/A

    Brain injury frequently results in cognitive impairment reducing an individual?s ability to judge driving situations accurately. Rehabilitation professionals use on-road tests to determine if an individual is safe to drive, but these tests are typically performed under calm conditions and offer little information on the individual?s responses to typical, real-life driving challenges. STISIM is a r ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  8. Rational Development of Thyroid Receptor Antagonists

    SBC: MOLSOFT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Molsoft proposes to develop antagonist lead molecules against the thyroid hormone receptor (TR) with IC50s in the low nanoM range and favorable bioavailability, specificity, and toxicity profiles. Proof of concept was achieved in Phase I Molsoft's virtual ligand screening technology allowed the discovery of 14 small molecule TR antagonists displaying extreme s ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. High Throughput Genotyping Technology

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The Molecular Inversion Probe technology has been developed to allow 1000 SNPs to be called in a single tube. This technology holds the promise of enabling large scale inexpensive genetic analysis including the analysis of whole genomes. Before such studies can be contemplated, further platform development is required. Software tools must be developed to proces ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Variation Scanning with Mismatch Repair Detection (MRD)

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One widely considered approach to identify susceptibility alleles is through linkage disequilibrium (LD) between these alleles and a universal set of relatively frequent SNPs distributed in all or most ethnic populations. This approach, however, may be unrealistic when variant alleles responsible for disease susceptibility are infrequent or are specific to a pa ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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