Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Developing a Small Peptide to Control Autoimmune Inflammation In Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    TypeDiabetesT Daffects an ever growing populationWhile this disease typically has been associated with juvenilesthe disease in adult populations is rapidly increasingThe defining clinical component is insulin losswhich occurs because of sustained inflammation in the isletsAt present there is no means to prevent or reverse insulin lossA major inflammatory pathway in T D that contributes to insulin ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. In Vivo Studies of a Novel HDAC Inhibitor for Treating Hemoglobin Disorders

    SBC: Cetya Therapeutics, Inc.            Topic: NHLBI

    PROJECT SUMMARY Thehemoglobinopathies are prevalent genetic blood diseases with few treatment optionsIt is estimate thatof the worldandapos s population carries an abnormal hemoglobin gene withinfants born annually with a severe life threatening hemoglobinopathyDrug mediated induction of normalbut developmentally silencedfetal hemoglobinHbFexpression reduces anemia and ameliorates clinical severit ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Innovative Mitigation of Radiation Effects in Advanced Technology Nodes

    SBC: Microelectronics Research Development Corporation            Topic: DTRA16A003

    Micro-RDC has developed portable radiation effects test structures that scale to new process nodes.These structures will enable the investigation of the effects of radiation on the new technology from the material processing level as well as the circuit level.Fabricating the chosen structures and the refinement of software to extract the model parameters will be completed in this effort.A suite of ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  4. ADA Conformable Wearable Battery-Hybrid Electrical Energy Storage System: A Rechargeable, Safe and High Performance Energy Storage Solution

    SBC: ADA Technologies, Inc.            Topic: A15AT010

    ADA Technologies, Inc. proposes to transition our previously developed BB-2590 Hybrid Electrical Energy Storage System (HEESS) architectureinto a Conformable Wearable Battery format, or CWB-HEESS (Figure 1). We seek to satisfy a meaningful, Army Program Executive Office (PEO) Soldier need for a rechargeable, safe and high energy CWB. We anticipate the CWB-HEESS will have broad U.S. Dept. of Defens ...

    STTR Phase II 2018 Department of DefenseArmy
  5. On Demand Energy Activated Liquid Decontaminants and Cleaning Solutions

    SBC: TDA Research, Inc.            Topic: A12AT005

    On-site activated decontaminants will revolutionize chemical and biological decon because the activated solution is produced on demand, without the limitations of traditional pre-made mixtures. TDAs system uses electrical activation to convert battery power into reactive chemicals that quickly destroy chemical and biological warfare agents. Prior to activation, the decontaminant mixture can be saf ...

    STTR Phase II 2018 Department of DefenseArmy
  6. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. THz Atmospheric & Ionospheric Propagation, Aborption and Scattering (TAIPAS) Model

    SBC: COLORADO ENGINEERING INC.            Topic: A09AT001

    Radio wave propagation models have steadily advanced during the past several decades producing what is widely recognized as a set of standard models for the attenuation, dispersion and nominal path of radio waves at frequencies within the radio region of the spectrum (i.e., which we define for these purposes as ~ 100 KHz to ~3 THz) with a focus on .1-1THz.Colorado Engineering, Inc. and the Univers ...

    STTR Phase II 2017 Department of DefenseArmy
  8. Chemical Kinetic Pathway Effects in Turbulent Reacting Flows

    SBC: REACTION SYSTEMS, INC            Topic: A16AT001

    The Army is very interested in accurate simulations of combustion in devices such as rockets and gas turbines, Otto and Diesel cycle IC engines, scramjet engines, rotating detonation engines, etc.The performance of weapons systems using these devices directly affect casualty/loss rates and the ability to win wars as well as procurement decisions and program costs. Accurate and computationally-affo ...

    STTR Phase II 2017 Department of DefenseArmy
  9. Scientific Merit and Feasibility of Fructokinase Inhibition for Obesity

    SBC: Colorado Research Partners LLC            Topic: 300

    Our goal is to develop a firstin class therapeutic agent that directly blocks the metabolism of fructosea key component in sugarIntake of sugarsucroseand high fructose corn syrupHFCSinduces metabolic syndrome and diabetes in laboratory animals and are strongly associated with obesity and diabetes in humansBoth sucrose and HFCS contain fructosewhich stimulates food intake by inducing leptin resista ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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