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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Microbial Synthesis of Therapeutic Bile Acids for Alzheimer's Disease
SBC: Metselex, Incorporated Topic: 105ABSTRACT This Phase STTR Phase II proposal aims to engineer and scale-up a synthetic metabolic pathway in a microbial host to produce UDCA and related compounds. Additionally, the UDCA produced from the engineered synthetic metabolic pathway will be used to synthesize derivatives for testing in our Alzheimer’s Disease cell and animal models. The proposed work has high intellectual merit for the ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
2-HOBA for Treatment of Pulmonary Hypertension
SBC: MTI Biotech Incorporated Topic: NHLBIPROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
An Interactive Education Program to Reduce High Risk Behavior in Adolescents
SBC: KLEIN BUENDEL, INC. Topic: NICHDInternet-based TRAC (i-TRAC): Interactive Emotion Regulation Skills Training to Improve AdolescentSexual Health Adolescence is a critical developmental period during which behavioral patterns are formed that have powerful influences on current and future health. This is particularly true for sexual behavior, which is affected by the biological changes of puberty as well as normative developmental ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
CCR4-IL2 Bispecific Immunotoxin for Targeted Therapy of Cutaneous T-Cell Lymphoma
SBC: ROCK IMMUNE LLC Topic: 102Abstract Cutaneous T-cell lymphoma (CTCL) is a type of extra-nodal non-Hodgkin’s lymphoma characterized by skinlesions resulting from infiltration of malignant T lymphocytes. Mycosis fungoides and Sezary syndrome are thetwo most common types of CTCL. Although treatments exist, they are mainly palliative with low response anddurability of response without any cure. The objective response rate rem ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Care Assistant for Family Caregivers of Persons with Dementia During Out of the Home Activities
SBC: Koronis Biomedical Technologies Corp. Topic: RAbstract Increases in life expectancy together with demographic trends have fueled a rapid increase in America’s elderly population. As the number of older Americans has grown, so has the prevalence of aging-associated diseases, including Alzheimer’s Disease (AD) and other related dementias (ADRD). An estimated 5.4 Million Americans had AD in 2012, and that number is expected to double by 2030 ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based- Phase II
SBC: KLEIN BUENDEL, INC. Topic: 102While studies support the efficacy of comprehensive, school-wide interventions in reducing bullying, these types of programs can require significant time and financial resources for implementation, resulting in barriers to providing school-based bullying prevention, especially in low-income and rural communities. Additionally, although training bystanders to act as “defenders” on behalf of tar ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Portable, affordable, quantitative microchip electrophoresis for hemoglobin A1C testing
SBC: HEMEX HEALTH INC Topic: 200PROJECT SUMMARY Diabetes is one of the most important health issues in the world. The number of people living with diabetes has quadrupled since 1980, with the greatest increase in prevalence in low and middle-income countries. Not only is diabetes a major cause of morbidity and mortality, but it can also devastate the finances of families and strain countries’ financial resources. World Health ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Smartphone App to Increase and Maintain Physical Activity in African American Men (FitBrothers)
SBC: KLEIN BUENDEL, INC. Topic: 102Physical activity (PA) is a modifiable risk factor for a number of preventable chronic diseases, including cardiovascular disease, strokes, obesity, and diabetes. These conditions constitute health disparities for African American men. Behavioral interventions have proven to be effective in promoting increases in physical activity. While behavior change programs have been shown to assist participa ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
3D Printed Multifunctional Brain Windows for Simultaneous Optical Imaging and Electrophysiology
SBC: APPLIED UNIVERSAL DYNAMICS, CORP Topic: 102PROJECT SUMMARY This proposal responds to PAR-18-870 titled “BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR).” This project is a Fast Track STTR with a phase I and phase II. The small business, Applied Universal Dynamics Corp. (AUD) is collaborating with the University of Minnesota (U of MN). The activity patterns of t ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Development of a treatment for the durable remission of HIV using autologous human CAR T cells that target B cell follicles
SBC: MARPAM PHARMA LLC Topic: NIAIDABSTRACT MarPam Pharma is developing a one-time treatment for durable remission of human immunodeficiency virus (HIV) for patients treated with antiretroviral therapy (ART). This treatment is an autologous HIV-specific chimeric antigen receptor (CAR; specifically, CD4-MBL-CAR) T cell therapy that employs the CXCR5 chemokine receptor as a homing device to direct anti-HIV killer T cells into “hidd ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health