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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microfluidic Technology for Concurrent Assessment of Red Blood Cell Adhesion and Deformability

    SBC: BIOCHIP LABS, INC.            Topic: NHLBI

    PROJECT SUMMARY Deformability and non-adherence are the most intrinsic biorheological properties of red blood cells (RBCs), as they play a critical role in modulating RBC perfusion through the microvasculature. In acquired or inherited blood disorders, such as sickle cell disease (SCD), these two interrelated properties are pathologically altered. SCD is an autosomal recessive disorder associated ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. An Interactive Education Program to Reduce High Risk Behavior in Adolescents

    SBC: KLEIN BUENDEL, INC.            Topic: NICHD

    Internet-based TRAC (i-TRAC): Interactive Emotion Regulation Skills Training to Improve AdolescentSexual Health Adolescence is a critical developmental period during which behavioral patterns are formed that have powerful influences on current and future health. This is particularly true for sexual behavior, which is affected by the biological changes of puberty as well as normative developmental ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. CCR4-IL2 Bispecific Immunotoxin for Targeted Therapy of Cutaneous T-Cell Lymphoma

    SBC: ROCK IMMUNE LLC            Topic: 102

    Abstract Cutaneous T-cell lymphoma (CTCL) is a type of extra-nodal non-Hodgkin’s lymphoma characterized by skinlesions resulting from infiltration of malignant T lymphocytes. Mycosis fungoides and Sezary syndrome are thetwo most common types of CTCL. Although treatments exist, they are mainly palliative with low response anddurability of response without any cure. The objective response rate rem ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Synthetic Aperture Radar(SAR) Image Generation Data Augmentation

    SBC: ETEGENT TECHNOLOGIES, LTD.            Topic: DTRA21B001

    Machine learning algorithms have demonstrated performance on par with or superior to human analysts on large datasets when sufficient training data is available.  For military applications obtaining sufficient, truthed data is always a challenge.  Three approaches have been used for measured data collections to support sensor exploitation programs: coordinated collections, turntable measurements ...

    STTR Phase II 2023 Department of DefenseDefense Threat Reduction Agency
  5. A dual-acting small molecule for the treatment of type 1 diabetes

    SBC: ASAKE BIOTECHNOLOGY, LLC            Topic: NIDDK

    Project Summary: Over 1.5 million Americans suffer from type 1 diabetes (T1D), an autoimmune disorder involving insulin, a hormone that is essential for blood glucose regulation and overall energy metabolism. When first diagnosed with T1D, it is estimated that the patient’s insulin has been reduced by 70-90%. By this point, the immune system has already targeted and destroyed a vast majority of ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. SciDAP: Scientific Data Analysis Platform

    SBC: DATIRIUM LLC            Topic: NHGRI

    The recent proliferation of next-generation sequencing (NGS) - based methods for the analysis of expression, chromatin and protein-DNA interactions has created tremendous opportunities for gaining insights into biology, health, and disease. However, analysis of the data requires computational expertise that many biologists do not possess. Hence, when dealing with genomics data, majority of biologi ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based- Phase II

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    While studies support the efficacy of comprehensive, school-wide interventions in reducing bullying, these types of programs can require significant time and financial resources for implementation, resulting in barriers to providing school-based bullying prevention, especially in low-income and rural communities. Additionally, although training bystanders to act as “defenders” on behalf of tar ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Endothelialized microfluidic assays for emerging therapies in sickle cell disease

    SBC: BIOCHIP LABS, INC.            Topic: NHLBI

    TBD

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Smartphone App to Increase and Maintain Physical Activity in African American Men (FitBrothers)

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    Physical activity (PA) is a modifiable risk factor for a number of preventable chronic diseases, including cardiovascular disease, strokes, obesity, and diabetes. These conditions constitute health disparities for African American men. Behavioral interventions have proven to be effective in promoting increases in physical activity. While behavior change programs have been shown to assist participa ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Phase II: In-field analysis of trace U and Pu by electrochemical pre-concentration

    SBC: AWAREABILITY TECHNOLOGIES, LLC            Topic: DTRA20B003

    The Defense Threat Reduction Agency (DTRA) needs a capability to collect and provide immediate presumptive analysis of radiological/nuclear samples of concern at the source of collection. Such in-field technologies should be capable of detecting and identifying trace quantities of elements and/or chemicals containing plutonium (Pu) and uranium (U), with a focus on chemicals specific to the nuclear ...

    STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency
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