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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. An Automated Patient Chart Error Detection System for Radiation Therapy

    SBC: Infondrian LLC            Topic: 101

    Project Summary Abstract Every yearapproximatelysevere mistreatments happen in radiation therapyRadiation therapy lawsuits rank in the top third of all medical specialties with an average of $per claim settled or litigatedThe current method for detecting treatment errors is by a weekly patient chart checkwhere each treatment record is manually reviewed on a weekly basisThis labor intensive and ine ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain Injury

    SBC: Mitovation, Inc.            Topic: 101

    Neonatal hypoxia ischemia is a known cause of cerebral damage resulting from inadequate blood flow and or oxygen delivery to the infant brain beforeduringor after birthThe occurrence among hospital deliveries isperfull term births with a drastic increase among premature newbornsThe deficit in oxygen delivery to the brain results in extensive damage and severe disabilitiesRestoration of blood flow ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. The Sustainable Heartland Accelerator Regional Partnership (SHARP) Hub

    SBC: BBC Entrepreneurial Training & Consulting, LLC            Topic: 500

    Project Summary Abstract Despite the investment of billions of dollars in biomedical research each year from NIHbarriers remain in effectively translating basic science discoveries from academia to commercial products that benefit patientsThese barriers include a funding gap between basic research and commercial developmentsa lack of knowledge by innovators on how to bring products to marketand a ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A nanoparticle delivery system for CRISPR/Cas9 based therapeutics

    SBC: ATGC Inc.            Topic: 100

    Abstract Applications of customizable nucleases such as CRISPRclustered regularly interspaced short palindromic repeatsCasCRISPR associated proteinhave enabled efficient and precise gene correction in vitroand hold promises for eventually achieving in vivo gene correction therapyHoweverto apply CRISPR Casin therapeutic settingsseveral major challenges remain to be addressedihomologous recombinatio ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Improving Outcomes for Mechanically Ventilated Patients with the Digital EZ Board

    SBC: VIDATAK, LLC            Topic: 600

    DESCRIPTION provided by applicant Effective communication between patients and healthcare professionals is essential to achieve positive clinical outcomes Patients who are unable to communicate effectively e g patients with limited English proficiency LEP those who are hearing impaired aphasic or have oral tracheal intubation experience extreme frustration panic anxiety sleeplessne ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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