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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. 2-HOBA for Treatment of Pulmonary Hypertension

    SBC: MTI Biotech Incorporated            Topic: NHLBI

    PROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. A Framework for mHealth App Security and Privacy Analysis

    SBC: UBITRIX INTERNATIONAL, INC.            Topic: NLM

    PROJECT SUMMARY/ABSTRACT With the increased use of mobile health (mHealth) apps to improve health outcomes, protecting private health data is becoming increasingly important. These mHealth apps are offered by healthcare providers and used by patients for various reasons such as paying bills, scheduling appointments, sending messages to providers, accessing lab results, and viewing prescriptions an ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Multispectral Sensor for Chemical Composition Analysis of Ultrafine Aerosols in Air Quality Assessment

    SBC: SPECTREE INC.            Topic: R

    Project SummaryWe propose developing and validating a novel platform technology that combines the collection and chemical analysis of ultrafine particles using an in-situ multispectral technique. The sample, collected directly onto the analysis substrate, is analyzed via excitation-emission matrix (EEM) spectroscopy. This approach will be validated against laboratory combustion-generated aerosols, ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development and Evaluation of Rosette Array Technology for HumanNeurodevelopmental Toxicity Screening

    SBC: Neurosetta LLC            Topic: R

    Project Summary Pre-clinical and pre-field toxicology testing of new drugs and chemicals does not routinely include direct assessment of human developmental neurotoxicity (DNT). Current standards for DNT testing require use of animal models with limited throughput and significant differences from human central nervous system (CNS) development. As such, many chemical products have required post-app ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Adjustable prosthetic sockets for children and adolescents with lower limb loss to accommodate growth

    SBC: IFIT PROSTHETICS, LLC            Topic: NICHD

    Pediatric limb loss, although relatively infrequent compared to adults, results in substantial hardship for children and their families. The principal business interest? iFIT Prosthetics, LLC®? successfully developed and manufactured innovative, fully adjustable, transtibial and transfemoral prosthetic devices, and demonstrated their safety, comfort, and functionality in adults. Made of injection ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Laser-based real-time Temperature Measurements in Detonation Environments

    SBC: EXMAT RESEARCH INC            Topic: DTRA19B001

    To support DTRA’s agent-defeat efforts, we will refine a laser-based Optical Thermocouple (OTC) technology and build and deliver to DTRA a hardened OTC prototype. This OTC system will be capable of quantifying the localized temporal evolution of temperature inside a detonation environment. The OTC technology is based on two-color fluorescence thermometry to determine the temperature. After laser ...

    STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency
  7. Enhancing the quality of CBT in community mental health through AI-generated fidelity feedback

    SBC: LYSSN.IO, INC            Topic: 104

    Each year, millions of Americans receive evidence-based psychotherapies (EBPs) such as cognitive behavioral therapy (CBT) for the treatment of mental and behavioral health problems. Yet, at present, there is no scalable method for evaluating the quality of psychotherapy services. In research settings, human-based behavioral coding methods are used, but these are time consuming, costly, and rarely ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. CBTpro: Scaling up CBT for psychosis using simulated patients and spoken language technologies

    SBC: LYSSN.IO, INC            Topic: 104

    Psychosis resulting from schizophrenia spectrum disorders and major mood disorders is one of the most disabling health concerns worldwide. Evidence-based psychotherapeutic interventions are recommended as standard of care by national psychosis treatment guidelines but are rarely accessible. Cognitive Behavioral Therapy for psychosis (CBTp) is the most well-researched psychotherapy for psychotic di ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development and Commercialization of a Sample Preparation System for Time Resolved Cryo-Electron Microscopy

    SBC: HUMMINGBIRD PRECISION MACHINE CO.            Topic: 400

    Cryo-electron microscopy (cryo-EM) is a powerful technique for imaging biological molecules in which samples are preserved in a frozen, hydrated state before imaging using an electron beam. The technique provides an alternative to X-ray crystallography for structural characterization of biological samples that are not crystallizable or do not crystallize in their native state. While cryo- EM sampl ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.

    SBC: Lumen Bioscience, Inc.            Topic: NIAID

    ABSTRACT Vaccination represents the single most effective and cost‐effective medical intervention devised to date, saving lives and reducing morbidity and disability for billions of humans. Despite the early success of the oral polio vaccine, most vaccines are delivered parenterally, and as such are associated with pain, non‐compliance, biohazardous medical waste and the need for trained medic ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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