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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Multispectral Sensor for Chemical Composition Analysis of Ultrafine Aerosols in Air Quality Assessment
SBC: SPECTREE INC. Topic: RProject SummaryWe propose developing and validating a novel platform technology that combines the collection and chemical analysis of ultrafine particles using an in-situ multispectral technique. The sample, collected directly onto the analysis substrate, is analyzed via excitation-emission matrix (EEM) spectroscopy. This approach will be validated against laboratory combustion-generated aerosols, ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of SP-A Derived Peptidomimetics for the Treatment of Asthma- Phase II
SBC: RaeSedo, LLC Topic: NHLBICurrent treatments for asthma, while reducing exacerbations in a subset of patients by focusing on airway inflammation, do not eliminate them. Asthma exacerbations are a significant cause of morbidity and mortality in asthma as they can lead to airway injury, lung function decline and death. Exacerbations in more severe asthmatics are of particular concern, as health care costs and lost productivi ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Critical angle reflection imaging for label-free quantification of molecular interactions
SBC: BIOSENSING INSTRUMENT INC Topic: 400TITLE: Critical angle reflection imaging (CARi) for label-free quantification of molecular interactions SUMMARYMeasuring molecular interactions of proteins are critical for understanding protein functions and cellular processes, for discovery and validating biomarkers, and for developing and screening drugs. In particular, membrane proteins play key roles in many cellular functions and are the lar ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Laser-based real-time Temperature Measurements in Detonation Environments
SBC: EXMAT RESEARCH INC Topic: DTRA19B001To support DTRA’s agent-defeat efforts, we will refine a laser-based Optical Thermocouple (OTC) technology and build and deliver to DTRA a hardened OTC prototype. This OTC system will be capable of quantifying the localized temporal evolution of temperature inside a detonation environment. The OTC technology is based on two-color fluorescence thermometry to determine the temperature. After laser ...
STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency -
Enhancing the quality of CBT in community mental health through AI-generated fidelity feedback
SBC: LYSSN.IO, INC Topic: 104Each year, millions of Americans receive evidence-based psychotherapies (EBPs) such as cognitive behavioral therapy (CBT) for the treatment of mental and behavioral health problems. Yet, at present, there is no scalable method for evaluating the quality of psychotherapy services. In research settings, human-based behavioral coding methods are used, but these are time consuming, costly, and rarely ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
CBTpro: Scaling up CBT for psychosis using simulated patients and spoken language technologies
SBC: LYSSN.IO, INC Topic: 104Psychosis resulting from schizophrenia spectrum disorders and major mood disorders is one of the most disabling health concerns worldwide. Evidence-based psychotherapeutic interventions are recommended as standard of care by national psychosis treatment guidelines but are rarely accessible. Cognitive Behavioral Therapy for psychosis (CBTp) is the most well-researched psychotherapy for psychotic di ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Development and Commercialization of a Sample Preparation System for Time Resolved Cryo-Electron Microscopy
SBC: HUMMINGBIRD PRECISION MACHINE CO. Topic: 400Cryo-electron microscopy (cryo-EM) is a powerful technique for imaging biological molecules in which samples are preserved in a frozen, hydrated state before imaging using an electron beam. The technique provides an alternative to X-ray crystallography for structural characterization of biological samples that are not crystallizable or do not crystallize in their native state. While cryo- EM sampl ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health -
eNamptorTM: A Humanized mAb To Reduce the Severity of Radiation Pneumonitis and Fibrosis
SBC: AQUALUNG THERAPEUTICS, CORP Topic: NHLBIABSTRACT The development of radiation-induced lung injury (RILI) is a potentially fatal toxicity in cancer patients undergoing thoracic radiotherapy or in individuals exposed to ionizing radiation (IR) from a nuclear incident. The pathobiology of radiation pneumonitis and radiation-induced lung fibrosis (RILF) is complex but includes the deleterious effects of unchecked inflammation (reactive oxyg ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health -
Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.
SBC: Lumen Bioscience, Inc. Topic: NIAIDABSTRACT Vaccination represents the single most effective and cost‐effective medical intervention devised to date, saving lives and reducing morbidity and disability for billions of humans. Despite the early success of the oral polio vaccine, most vaccines are delivered parenterally, and as such are associated with pain, non‐compliance, biohazardous medical waste and the need for trained medic ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health -
Development of Non-Catalytic Peptide Inhibitors of Focal Adhesion Kinase (FAK) for Use in Melanoma
SBC: Faknostics, LLC Topic: 102Abstract Melanoma is the deadliest form of skin cancer, affecting an estimated 1.2 million Americans. The disease has a high propensity for dissemination, and metastatic melanoma has a dismal prognosis, with a median survival of only 5–8 months. Healthcare costs for melanoma in 2021 are projected to reach nearly $4 billion, with a rising incidence rate. Despite considerable efforts in recent yea ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health