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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A2A receptor blockade for sepsis
SBC: Purine Pharmaceuticals Inc. Topic: NIAIDSUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
microRNA-21 Blockade of Triple Negative Breast Cancer
SBC: BOUND THERAPEUTICS LLC Topic: 102Triple negative breast cancerTNBCis an orphan disease that attacksUS women every yearTNBC cells lack human estrogen receptorprogesterone receptorand epidermal growth factor receptorHerthe targets of existing medicinesTNBC recurs after standard of care chemotherapy and radiationkilling its victims withinyearsNew promising therapies such as poly ADP ribosepolymerasePARPinhibitors only benefit a smal ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes
SBC: CellGro Technologies, LLC Topic: 400PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
PreImplantation Factor plus hypothermia to treat neonatal brain injury
SBC: BioIncept, LLC Topic: NICHDABSTRACTPerinatal hypoxic ischemic encephalopathyHIEaffectstoinfants per everybornMortality from HIE can be up toand approximatelyof survivors suffer significant longterm disability including cerebral palsyepilepsyand developmental disordersDamage during the acute phase of HIE is caused by a deficit in oxygen and glucose in the brainHoweverincreasing evidence indicates that secondary and tertiary ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Antimicrobial Foley Catheter to Prevent CAUTIs
SBC: HYDROMER, INC. Topic: NIDDKDESCRIPTION (provided by applicant): Catheter-associated urinary tract infections (CAUTI) are a leading cause of hospital-acquired infections and lead to increased costs, suffering and mortality. A primary contributor to CAUTI is formation of bacterial biofilms on indwelling catheters. Biofilms are inherently resistant to most antibiotics, and once established serve as a bacterial reservoir propag ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Mucins in the Diagnosis and Prognosis of Pancreatic Diseases
SBC: Sanguine Diagnostics And Therapeutics, Inc. Topic: NCIDESCRIPTION (provided by applicant): Due to its asymptomatic nature and lack of methods for early detection, gt 80% of pancreatic cancer (PC) patients present with an unresectable primary tumor with distant metastasis at the time of diagnosis. While the overall 5 year survival rate of pancreatic cancer is dismal, significantly better outcomes have been reported for smaller tumors detected at an e ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Use of EF2K Inhibitors to Reduce Toxicity to Normal Tissues in Chemotherapy
SBC: LONGEVICA PHARMACEUTICALS, INC. Topic: NCIDESCRIPTION (provided by applicant): Eukaryotic elongation factor 2 protein kinase (eEF2K) is a ubiquitously expressed protein that belongs to a family of alpha kinases characterized by an atypical kinase domain. Our recent findings demonstrate that inhibition or genetic inactivation of eEF2K protects normal tissues from cytotoxic effects of chemotherapeutic agents and ionizing radiation. We hav ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Silica Colloidal Crystals for High Resolution MALDI-MS of Glycoproteins
SBC: LI-COR, Inc. Topic: 100DESCRIPTION provided by applicant The product is a slide coated with silica colloidal crystals to combine protein electrophoresis with matrix assisted laser desorption ionization mass spectrometry MALDI MS detection giving superior performance in both The Phase II proposal will be to develop an instrument for facile application of the slide in proteomics of intat glycoproteins This propos ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Targeting B-cell lymphoma with Leukothera-phase II
SBC: Actinobac Biomed, Inc. Topic: NCIDESCRIPTION provided by applicant B cell lymphoma is cancer of B lymphocytes and accounts for more than deaths in the U S each year While many patients respond to currently available therapy there is a high rate of cancer relapse and inability for the patients o tolerate chemotherapy Thus there is a significant need to make available to these patients newer therapies that are more e ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES
SBC: FIREFLY HEALTH INNOVATIONS NE, INC. Topic: NIDCRDESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health