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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Measurement of Beta Cell Death in Diabetes

    SBC: L2 Diagnostics, LLC            Topic: 200

    DESCRIPTION provided by applicant All forms of diabetes are characterized by the death of insulin producing cells In Type diabetes T D this leads to the reliance on exogenous insulin for survival Death of cells is silent it cannot be detected in vivo until it has progressed to such an extent that metabolic function is impaired The loss of cells has only been assessed by functiona ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A serologic assay to measure successful Lyme borreliosis antibiotic therapy

    SBC: L2 Diagnostics, LLC            Topic: R

    DESCRIPTION provided by applicant Lyme disease LD caused by the Ixodes tick borne spirochete Borrelia burgdorferi Bb is the most common vector borne disease in the United States Despite public health preventive measures the annual confirmed case incidence has risen to over the vast majority of which occur in the Northeast Disseminated infection causes disease in the skin heart ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Synthetic microparticle malaria vaccine

    SBC: ARTIFICIAL CELL TECHNOLOGIES INC            Topic: NIAID

    DESCRIPTION provided by applicant This Phase II project will develop a novel synthetic microparticle vaccine for malaria using the T BT epitopes of the circumsporozoite CS protein of Plasmodium falciparum the causative agent of human malaria There is no approved vaccine for malaria a disease that causes up to million new infections and million deaths each year in the developing wor ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Diagnostic Assays for early Lyme Borreliosis using in-vivo expressed antigens

    SBC: L2 Diagnostics, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Current testing for Lyme disease is suboptimal because it requires two assay platforms including one with subjective interpretation of results and because it has lower sensitivity in the early stage of the illness Infection with Borrelia burgdorferi the causative agent of Lyme disease is transmitted by the bite of an Ixodid tick and results in uniformly lo ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Vault-CCL21 Nanocapsule for Lung Cancer

    SBC: PROTEIN SCIENCES CORPORATION            Topic: NCI

    DESCRIPTION provided by applicant Lung cancer is the leading cause of cancer death in the United States and is responsible for more deaths each year than breast prostate colon hepatic renal and skin cancers combined Viewed in economic terms in the United States the value of life lost from lung cancer deaths in the year was more than $ billion which is estimated to rise to more t ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. software to translate behavioral economic insights to improve health

    SBC: VAL Health, LLC            Topic: NIA

    DESCRIPTION provided by applicant Unhealthy behaviors such as smoking medication non adherence and lifestyle habits leading to obesity are major contributors to premature morbidity and mortality among the U S population Participation rates in programs designed to improve these behaviors are often less than Considerable research has shown that lotteries that leverage the principle of an ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Saliva Analyzer for Diagnosing SRD Patient Drug Use

    SBC: REAL-TIME ANALYZERS, INCORPORATED            Topic: NIDA

    DESCRIPTION provided by applicant The overall aim of this SBIR program is to develop a surface enhanced Raman spectroscopy SERS based device for point of care analysis of drugs in patient saliva This device will allow immediate assessment of both prescription and illicit drug use by patients with substance related disorders SRDs and provide medical professionals and management with quanti ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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