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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Long Circulating Liposomal Camptothecins CAP and EAP
SBC: TIGEN PHARMACEUTICALS Topic: N/ADESCRIPTION (provided by applicant): Based on the extensive data generated during the phase I portion of our studies, there is sufficient and compelling information to support the further development of the highly lipophilic and blood-stable topoisomerase inhibitor, DB-67. In part, the pre-clinical and clinical evaluation of DB-67 is currently being supported by ...
STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health -
PRECISE 3D QCT TO MONITOR OSTEOPOROSIS THERAPY
SBC: IMAGE ANALYSIS, INC. Topic: N/ADESCRIPTION (provided by applicant):The growing number of women receiving drug treatment for osteoporosis underscores the need for sensitive methods to monitor therapy. Because it permits selective assessment of the trabecular and cortical bone, which may respond differently to disease and therapy, quantitative computed tomography (QCT) is well-suited to this purpose. However, the ability of QCT t ...
STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health -
Method to Guarantee the Quality of Radiotherapy Planning
SBC: ADVANCED PROCESS COMBINATORICS, INC. Topic: N/ADESCRIPTION (provided by applicant): This project will develop a package of planning products for radiation treatment that will introduce a measure of quality assurance now lacking, provide clinicians the opportunity to raise tumor dose, and expose the tradeoffs among the treatment constraints and objectives. The new approach based on mixed integer programming (MIP) will ensure that the dose distr ...
STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health -
Anatomy of the Central Nervous System-Multimedia Course
SBC: ORCCA TECHNOLOGY, INC. Topic: N/ADESCRIPTION (provided by applicant): This project will develop, evaluate and distribute an interactive multimedia program to provide interactive instruction about the human nervous system using a programmed learning format. The program will also provide extensive self-testing for the competencies to be acquired through interaction with the software program. The specific aims of the project are: A) ...
STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health -
Biomolecule Crystallization Microarray
SBC: TECHSHOT, INC. Topic: N/ADESCRIPTION (provided by applicant): Several aspects of health and medicinal research depend on the knowledge of macromolecular structures, the determination of which depends on a supply of high-quality crystals. Conditions for growing high-quality crystals are usually determined by expensive trial-and-error research. The proposed innovation is a lithography-fabricated system for automated, kinet ...
STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health -
Modeling Languages and Analysis Tools for Complex Distributed
SBC: Fremont Associates, LLC Topic: AF04T023The Architecture Analysis and Design Language (AADL) is an SAE standard language for describing the software and hardware architecture of performance-critical real-time systems. In addition, the AADL standard allows the definition of annexes, i.e., formal extensions to the standard language to enhance the design specifications of hardware or software components. We propose to leverage the AADL la ...
STTR Phase II 2005 Department of DefenseAir Force -
Novel accelerated in vitro breeding for phytoremediation
SBC: SOUTHERN SUN BIOSYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): The long-term goal of the collaboration between the USC and Southern Sun BioSystems is to create a plant breeding and remediation technology-development center which would supply hardware, protocols for breeding-selection and mass production of elite plants for nurseries and remediation businesses, with licensing and tracking mechanisms for protecting intellect ...
STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Transgenic plant cells as a source of hepatoprotective drugs
SBC: NAPROGENIX, INC. Topic: N/ADESCRIPTION (provided by applicant): Alcoholic liver damage (ALD) is among the top ten causes of death in the USA, but existing therapeutic interventions are relatively ineffective. Hepatocytes are susceptible to damage probably because they have a high level of alcohol dehydrogenase (ADH) which metabolizes alcohol to form acetaldehyde and reactive oxygen species (ROS), which are both cytotoxic. C ...
STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health -
Enhancement of the baculovirus expression vector system
SBC: PARATECHS CORP Topic: N/ADESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) is one of the most powerful and versatile eukaryotic expression systems. The BEVS is being used to produce antigens for vaccine development, to manufacture human therapeutics, to develop faster acting biological insecticides, and as a protein expression system for a multitude of research projects. However, a limit ...
STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health -
Hypericum extracts as potential anti-relapse medications in alcoholism
SBC: NAPROGENIX, INC. Topic: N/ADESCRIPTION (provided by applicant): Alcoholism is a complex disease and anti-relapse treatments should recognize this. For example, depression is a frequent precipitant of relapse (1) and is the most common co-morbid psychiatric disorder in alcoholism. An anti-relapse agent with antidepressant properties might therefore be valuable, specifically for this large subpopulation. In this regard, the e ...
STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health