Award Data

DESCRIPTION (provided by applicant):Reliable operation of a portable defibrillator depends critically on the "condition" of its battery. This condition is determined by available energy and at what power level this energy can be delivered to a load. With the initiative towards widespread deployment of portable defibrillators, a low-cost device capable of accurately measuring both state-of-charge ( ...

Crested multi-layer tunnel barriers have been proposed, which offer a revolutionary solution to overcome density to speed trade-offs characteristic of present data storage technologies. Practical implementation of the proposed technology will involve useof thin film materials that are readily manufacturable and CMOS-compatible. A critical need exists for experimental verification of the theoreti ...

The Architecture Analysis and Design Language (AADL) is an SAE standard language for describing the software and hardware architecture of performance-critical real-time systems. In addition, the AADL standard allows the definition of annexes, i.e., formal extensions to the standard language to enhance the design specifications of hardware or software components. We propose to leverage the AADL la ...

DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a significant proportion of serious hospital acquired infections. The organism has intrinsic resistance to most types of antibiotics and can readily acquire resistance to all clinically available antimicrobials, resulting in infections that are impossible to treat. P. aeruginosa colo ...

Sonalysts, Inc. and the University of Connecticut have developed a proof-of-concept prototype for a cross-disciplinary, efficient stream data mining and intelligent storage system that is portable and configurable for systems that ingest huge data streams and determine what data to store where. For the Phase II research, Sonalysts will build upon the prototype development to receive actual incomi ...

In colloidal propulsion, there have been significant improvements in 1-D micro-fabricated arrays operating in the single Taylor cone per emitter regime. Unfortunately, this arrangement necessitates the construction of very large colloidal thrusters inefficiently utilizing a limited amount of area to produce suitable thrust. To maximize the density of individual colloidal emitters per unit area, ...

DESCRIPTION (provided by investigator): The medication dispensing and monitoring system, MD 2, has been shown in preliminary studies to support a medication compliance rate of 98.5% The MD 2 was developed by Interactive Medical Developments LC to address issues of medicine non-compliance and the negative impact non-compliance has on the health and well being of the patient and the frustration of c ...

DESCRIPTION (provided by applicant): Breast cancer remains one of the most insidious and difficult to treat human malignancies, affecting thousands of individuals each year. Our proposed studies are aimed at developing a novel tumor immunotherapy by using cryptic peptides of Her-2 protein and modified Her-2 peptides, both of which break immune tolerance to ?self? tumor antigens expressed on breast ...

DESCRIPTION (provided by applicant): The long-term goal of the collaboration between the USC and Southern Sun BioSystems is to create a plant breeding and remediation technology-development center which would supply hardware, protocols for breeding-selection and mass production of elite plants for nurseries and remediation businesses, with licensing and tracking mechanisms for protecting intellect ...

DESCRIPTION (provided by applicant): Phase I The current proposal describes the selection of an aptamer that recognizes the drug PD173955, which is one of large family of substituted pyrido[2,3-d]pyrimidine inhibitors of tyrosine protein kinases. An aptamer is a single stranded nucleic acid that acts like an antibody but that can be expressed and function inside cells. The PD173955 RNA aptamer wi ...