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"The proposed Phase 2 program focuses on the development of Powered Resonance Tube (PRT) actuators for application to Active Flow Control (AFC). For effective control across the full operating envelope of an air vehicle, high bandwidth and authority arerequired. In Phase 1, a new variable-frequency PRT actuator concept was developed and its feasibility was demonstrated. In Phase 2, the new actu ...

DESCRIPTION (provided by applicant): We have developed several tumor-specific and tissue-specific replication-competent adenoviruses (Ad) vectors for cancer gene therapy. One vector, named KD3, has a mutation in the E1A gene such that KD3 cannot replicate in, and destroy, "normal" cells. However, KD3 can replicate in cancer cells because they have a microenvironment conducive to KD3 replication. ...

Military aircraft are largely constructed from special aluminum alloys, which typically have secondary precipitate phases that substantially improve mechanical strength. However, these regions also promote corrosion in such common environmental conditionsas acid rain, saltwater, and thermal cycling. The problem is significant enough that the U.S. Air Force expends approximately $1 billion per year ...

The proposed Phase II effort will result in the development of new devices for improving optical propagation of both directed energy and free space communication systems. The Phase I effort has demonstrated the feasibility of these devices. The Phase II effort will provide the optimization and maturation needed to bring them to the commercial markets through two paths. The first is a high frequ ...

The Architecture Analysis and Design Language (AADL) is an SAE standard language for describing the software and hardware architecture of performance-critical real-time systems. In addition, the AADL standard allows the definition of annexes, i.e., formal extensions to the standard language to enhance the design specifications of hardware or software components. We propose to leverage the AADL la ...

We propose to develop a computer based system for the online analysis of bio-behavioral signals associated with momentary loss of alertness. We will continue our development of bio-behavioral measures indicative of lapses in alertness. Our system will use only measures that can be obtained without attaching sensors to the operator. We will concentrate on monitoring the oculomotor system using came ...

DESCRIPTION (provided by applicant): The long-term goal of the collaboration between the USC and Southern Sun BioSystems is to create a plant breeding and remediation technology-development center which would supply hardware, protocols for breeding-selection and mass production of elite plants for nurseries and remediation businesses, with licensing and tracking mechanisms for protecting intellect ...

DESCRIPTION (provided by applicant): Databases of biological sequences have proven valuable for understanding the organization of human and other genomes, for unraveling the etiology of genetic disorders, and for studying medically important pathogens. Unfortunately, these databases are growing at an exponential rate, posing a severe problem for bio-sequence annotation. Specialized hardware implem ...