Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons

    SBC: SensoDX II, LLC            Topic: NIDA

    Abstract Opioid abuse disorderOADaffectsmillion of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortalityIn addition to its enormous social impactOAD carries a multi billion dollar price tag that includes $billionspecifically for health care and other costs related to prescription opioid abuse and misuseAlthough effective interventions exis ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Highly selective detection of tau oligomers in biological fluids for the diagnosis of Alzheimer's Disease

    SBC: Amprion, Inc.            Topic: NIA

    This proposal is for a phase I II fast track project for the STTR program with the main goal to develop a test for high sensitive detection of tau oligomers in biological fluidswhich could be used for the biochemical diagnosis of Alzheimer s diseaseADand related tauopathiesAD is the most common dementia in the elderly population and one of the leading causes of death in the developed worldOne of t ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Preclinical Development of OCF001 for Treatment of Yeast Infections

    SBC: Sano Chemicals, Inc.            Topic: NIAID

    Project Summary OccidiofunginsA Dare cyclic nonribosomally synthesized antifungal peptides with submicromolar fungicidal activity against a broad spectrum of fungiOptimization of the production and isolation of occidiofungins from liquid cultures has been performedThe production and isolation of predominantly one analogcalled occidiofungin BOCFsupports its commercial development as a novel antifun ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Developing an automated yeast dissection system for aging research

    SBC: Innovative BioChips LLC            Topic: NIA

    PROJECT SUMMARY Developing an Automated Yeast Dissection System for Aging ResearchAging is the single greatest risk factor for diseases that are principal causes of mortalityThe objectives of aging research are to discover key genes and pathways related to aging that may eventually contribute to retardation of aging and a delay in the onset of age associated diseasesThe budding yeast Saccharomyces ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Midwave Infared (MWIR) Quantum Cascade Lasers (QCL) Thermal Monitoring

    SBC: Max-IR Labs, LLC            Topic: AF17AT026

    Max-IR Labs LLC, in collaboration with UT Dallas, successfully demonstrated construction and operation of a prototype Infrared Near-Field Scanning Optical Microscopy (IR-SNOM) instrument for high-spatial-resolution thermal mapping of small heat sources, in particular Quantum Cascade Laser (QCL) facets, during Phase I.Preliminary data demonstrated feasibility of implementation of this instrument an ...

    STTR Phase II 2018 Department of DefenseAir Force
  6. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a small molecule activator of integrin cell adhesion to enhance therapeutic responses to checkpoint blockade in cancer

    SBC: 7 Hills Pharma LLC            Topic: 102

    Recent FDA approvals of ipilimumabnivolumaband pembrolizumabwhich target checkpoint receptors cytotoxic T lymphocyte associated antigenCTLAand programmed deathPDhave ushered in a new era of cancer immunotherapy in metastatic melanomaDespite unprecedented overall survival benefits with combination therapythe incidence of complete responses are onlyimmune related adverse eventsirAEsare increasedand ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Biomimetic Design of Morphing Micro Air Vehicles

    SBC: Texas Research Institute, Austin, Inc.            Topic: AF15AT01

    Over the past two decades significant progress has been made on the development of mission capable micro air vehicles (MAV) and small unmanned aircraft systems (sUAS) but the full potential of implementing multifunctional morphing wings using active materials has not been realized.A need exists to develop a MAV wing that can autonomously adapt to flight conditions allowing the vehicle to aggressiv ...

    STTR Phase II 2018 Department of DefenseAir Force
  9. Training Environment for Design of Resilient Systems (TENSILITY)

    SBC: G&C SYSTEMS, INC.            Topic: AF16AT08

    The main objective for Knowledge Based Systems, Inc. (KBSI) for this project is to develop the Training Environment for Design of Resilient Systems (TENSILITY) method and supporting framework to enable Platform Information Technology (PIT) and PIT systems designers, systems designers, systems integrators, systems test and evaluation (T&E) engineers, and hardware, firmware and software developers t ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Plenoptic Fluid Density Imaging

    SBC: NANOHMICS INC            Topic: AF16AT06

    Instantaneous volumetric fluid imaging is crucial to high-speed aerodynamic development and testing.Rapid three-dimensional (3D) measurement of fluid density enables accurate capture of dynamic flow phenomena for validation of computational fluid dynamics (CFD) simulations in wind tunnels.Nanohmics, Inc., teaming with the University of Texas (UT) Flowfield Imaging Laboratory, has developed the fir ...

    STTR Phase II 2017 Department of DefenseAir Force
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