Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Reversal of Myocardial Infarction by Localized Stimulation

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Failure Initiation Prediction for Reliability-Based Design of Hybrid Composite Materials

    SBC: Firehole Technologies, Inc.            Topic: AF08T025

    The objective of this project is to develop extensions to Multicontinuum Technology (MCT) that enable accurate and efficient analysis of textile composite structures. In addition, probabilistic analyses will be performed to demonstrate the applicability of MCT for textile composite material selection and structure design. The project will build on the successful two-constituent MCT by generalizi ...

    STTR Phase II 2010 Department of DefenseAir Force
  5. High-order modeling of applied multi-physics phenomena

    SBC: SCIENTIFIC SIMULATIONS            Topic: AF08T023

    A new physics-based simulation capability will be developed based on high-order discretizations in both space and time for application to practical engineering problems involving complex physical phenomena and complicated geometries. The goal is to develop a tool which can accurately handle simulations of various important physical problems relevant to the aerospace industry and the DoD, including ...

    STTR Phase II 2010 Department of DefenseAir Force
  6. Modeling Languages and Analysis Tools for Complex Distributed

    SBC: Fremont Associates, LLC            Topic: AF04T023

    The Architecture Analysis and Design Language (AADL) is an SAE standard language for describing the software and hardware architecture of performance-critical real-time systems. In addition, the AADL standard allows the definition of annexes, i.e., formal extensions to the standard language to enhance the design specifications of hardware or software components. We propose to leverage the AADL la ...

    STTR Phase II 2005 Department of DefenseAir Force
  7. Hybrid CMOS/Nanodevice Integrated Circuits

    SBC: Sensor Electronic Technology, Inc.            Topic: AF07T025

    We propose to develop a novel hybrid circuit approach combining CMOS and two terminal crosspoint nanodevices with a novel interface consisting of an array of pins with nanometer scale tips. Our CMOL approach will allow the fabrication of ultra-dense integrated circuits (up to 10^12 active devices per cm2) for advanced computing (up to 10^20 operation per cm2 per second), information storage and se ...

    STTR Phase II 2009 Department of DefenseAir Force
  8. Highly-Scalable Computational-Based Engineering Algorithms for Emerging Parallel Machine Architectures

    SBC: SCIENTIFIC SIMULATIONS            Topic: AF10BT13

    ABSTRACT: In order to significantly advance the fidelity and capability of current computational engineering tools, algorithms, techniques, and software which map effectively to emerging massively parallel hardware architectures must be developed. The objective of this project is to investigate and demonstrate specific techniques for enhancing the scalability of computational fluid dynamics (CFD) ...

    STTR Phase II 2013 Department of DefenseAir Force
  9. Sensitivity Analysis Methods for Complex, Multidisciplinary Systems

    SBC: SCIENTIFIC SIMULATIONS            Topic: AF11BT06

    ABSTRACT: The objective of this proposal is to develop efficient sensitivity analysis methods based on adjoint techniques for multi-disciplinary time-dependent problems. The approach is based on the discrete adjoint, which is derived and implemented on a software component basis, with the various multidisciplinary software components being linked together through a Python interface, thus preservi ...

    STTR Phase II 2014 Department of DefenseAir Force
  10. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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