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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IMMUNOLIPOSOME-MEDIATED GENE THERAPY FOR PROSTATE CANCER

    SBC: SYNERGENE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Advanced prostate cancer tends to be relatively refractory to standard chemotherapeutic agents and radiation treatment, and this resistance correlates with a lack of functional p53. Our previous data indicate that cancer cells can be sensitized to radiation and chemotherapy via p53 replacement using a tumor-targeting liposomal delivery system. In the STTR Phase ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  2. Plasma Wave Electronics

    SBC: Sensor Electronic Technology, Inc.            Topic: ARMY03T06

    Terahertz plasma wave detectors and emitters utilizing the high-density 2-D electrons in submicron AlGaInN/GaN-based Quantum Well Heterostructure Field Effect Transistors (QW-HFETs)with high-sensitivity levels for the sensing of terahertz (THz) frequency electromagnetic radiation are proposed and developed.

    STTR Phase II 2004 Department of DefenseArmy
  3. A Dual Molecular/Tumor Targeting Therapy for PanCa

    SBC: SYNERGENE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 30,000 people in the United States are diagnosed each year with pancreatic cancer (PanCa). Over 90% of these will die of the disease making PanCa one of the most devastating human malignancies. The current 5-year survival rate of less than 4% has changed little in the last 20 years despite improvements in therapy including the introduction of ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Novel accelerated in vitro breeding for phytoremediation

    SBC: SOUTHERN SUN BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of the collaboration between the USC and Southern Sun BioSystems is to create a plant breeding and remediation technology-development center which would supply hardware, protocols for breeding-selection and mass production of elite plants for nurseries and remediation businesses, with licensing and tracking mechanisms for protecting intellect ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Optimal Design of Compact Fuel Cell Hybrid Power Systems

    SBC: INTERACTIVE DATA VISUALIZATION            Topic: A06T014

    This work will continue the use of numerical methods to determine optimal design parameters for a compact hybrid fuel cell power system driven by a statistically determined load profile. Detailed physics-based models will be used to represent the bahavior of the components in the hybrid system. The components considered in the hybrid system for Phase II will be a PEM fuel cell, Li-ion batteries an ...

    STTR Phase II 2007 Department of DefenseArmy
  6. Restoration of Skin Structure and Function Post-Wounding

    SBC: FirstString Research, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The wound repair process in skin is initiated immediately after an injury and induces a cascade of events including inflammation, proliferation, and scar differentiation. The adverse changes in skin structure and function resulting from scar tissue affects over 35 million US citizens a year resulting in costs of more than 7 billion dollars). The founders of Fir ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. A synthetic biology library for the Semantic Web

    SBC: Clark & Parsia, LLC            Topic: NHGRI

    DESCRIPTION (provided by applicant): The long-term aims of this project are to improve the engineering practices of synthetic biologists, and thereby to hasten the pace of synthetic biology research. Synthetic biology is poised to make great contributions to health, medicine, energy, and the environment by building systems ranging from the production of anti-malarial drugs, to improved antibiotics ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Continuous monitoring of anti-fibrinolytic therapy in cardiovascular surgery

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): A major cause of morbidity and mortality in cardiovascular surgery is excessive bleeding post- operatively, which is commonly managed by pharmacologically modifying clot degradation (fibrinolysis), through inhibition of plasmin activity (PLact). However, the only FDA approved and most commonly used inhibitor of PLact in cardiovascular surgery, while effective i ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  9. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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