Award Data

The fabrication of submicron piezoelectric ceramics (PZT-5) with properties comparable to commercially available coarse grained materials was demonstrated in the Phase I Small Business Technology Transfer (STTR) program. This work was accomplished in collaboration with the Pennsylvania State University, through a fundamental understanding of the domain state in these materials. Specifically, novel ...

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This Phase II STTR proposal describes the development of a prototype enzyme-containing adhesive capable of attaching biocatalytic activity directly to skin. The adhesive, when containing organophosphorus-hydrolyzing enzymes, shall serve to protectunderlying skin from otherwise toxic applications of nerve agents and pesticides. Agentase, a recognized world leader in developing polymer-based carri ...

Kigre's Phase I fiber amplifier development effort demonstrated 10dB of internal gain at 1.54um from 2.2 cm long section of MM-2 erbium ytterbium phosphate fiber amplifier pumped at 980nm. 26dB of gain was also produced from a 8.8com long section of thissame fiber pumped at 1480nm. Mode field image testing of a fiber show this MM-2 fiber to be perfect 1.54um single mode containment match to stan ...

The objective of the work proposed herein is to develop innovative methodologies and techniques for the use of 3D woven composites with enhanced structural and ballistic characteristics for wide ranges of armor and structural applications. A family of 3Dintegrally woven composites, which utilizes multi-axial weave designs, have been examined and analyzed in the Phase I study. These innovative 3D ...

Serenix Pharmaceuticals LLC (SPL) will develop drugs to treat impulsivity, violence and self-injurious behavior in patients with autism, Tourette's syndrome, and mental retardation. These drugs, termed serenics, stop violent behavior without disrupting normal behaviors. No other products are available for these indications. SPL required a series of vasopressin receptor antagonists from Eli Lilly C ...

"High-performance sintered rare earth magnets are based on intermetallic compounds of SmCo5, Sm2Co17, or Nd2Fe14B. Each of these compounds is intrinsically brittle and can only be shaped by grinding, lapping, and electro-discharge machining (EDM). Evengrinding and lapping these magnets to the required dimensions often results in chipping, cracking, or fracture, leading to production losses rangi ...

Brain damage from hypoxia-ischemia represents a major health problem in pediatrics. At present, no method exists in clinical care to diagnose cerebral hypoxia-ischemia in real-time at the bedside, thereby limiting prevention and treatment of the brain damage. Near infrared spectroscopy (cerebral oximetry) is an emerging optical technology with the potential to fulfill this role. In previous work, ...