Award Data

DESCRIPTION (provided by applicant): Dialectical Behavior Therapy (DBT) is a multimodal, psychosocial treatment with demonstrated efficacy in treating borderline personality disorder (BPD). In Phase I, we developed and evaluated a pilot videotape of Marsha M. Linehan, Ph.D., teaching a DBT emotion regulation skill. Results demonstrated the videotape's efficacy at impa ...

DESCRIPTION: (taken from the abstract) The goal of this Phase II Small Business Technology Transfer Grant Application is to build and evaluate a commercial quality orthodontic Headgear Monitoring System that provides a quantitative measure of a patient's headgear use (both time and force). The Headgear Monitoring System consists of a headgear monitor, a communic ...

DESCRIPTION (provided by the applicant): High Intensity Focused Ultrasound (HIFU) offers a non-invasive, non-surgical, bloodless, outpatient treatment for uterine fibroid tumors. These tumors develop in over half of all women, and account for approximately 30 percent of all hysterectomies. This proposal will develop an integrated transvaginal HIFU probe and imaging transducer for fibroid treatment ...

DESCRIPTION (provided by applicant):Reliable operation of a portable defibrillator depends critically on the "condition" of its battery. This condition is determined by available energy and at what power level this energy can be delivered to a load. With the initiative towards widespread deployment of portable defibrillators, a low-cost device capable of accurately measuring both state-of-charge ( ...

To be commercially competitive, PEM fuel cells have to be able to run on readily available fuels. Fuel reformers are practical, but fuel cell anode catalysts are severely poisoned by small quantities of carbon monoxide from the reformer. Despite mucheffort invested into increasing CO tolerance, desired performance levels have not been achieved.Our Phase I data has demonstrated excellent CO-toler ...

The overall objective of this Phase II program is to produce, by the end of the two-year effort, a low-cost, ready-to-use, field-deployable simple kit comprising paper, wood or plastic strips that detect the principal chemical warfare agents (CWAs) - Mustard, Sarin, Soman, and VX - in liquid as well as vapor forms, by fast and dramatic color changes. Our Phase I work produced prototype demonstra ...

Terahertz plasma wave detectors and emitters utilizing the high-density 2-D electrons in submicron AlGaInN/GaN-based Quantum Well Heterostructure Field Effect Transistors (QW-HFETs)with high-sensitivity levels for the sensing of terahertz (THz) frequency electromagnetic radiation are proposed and developed.

During Phase I Sonalysts, Inc., Worcester Polytechnic Institute, and Advanced Interactive Simulations, collaborated to investigate the feasibility of producing a training system that, using a simulated urban environment, supplies instructional interventions (such as real-time feedback) that are pedagogically sound and contextually relevant to the Soldier engaged in first-person simulated training. ...

DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a significant proportion of serious hospital acquired infections. The organism has intrinsic resistance to most types of antibiotics and can readily acquire resistance to all clinically available antimicrobials, resulting in infections that are impossible to treat. P. aeruginosa colo ...

DESCRIPTION (provided by applicant): The high cost ($0.8 - $1.7 billion) and long time frames (about 13 years) required to introduce new drugs to the market contributes substantially to spiraling health care costs and diseases persisting without effective cures. A major factor is the high attrition rate of new compounds failing due to toxicity identified years into clinical trials. This particular ...