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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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An Efficacy Trial of Mobile Technology for Reducing and Preventing Adolescent Suicide
SBC: OUI THERAPEUTICS INC Topic: 104ABSTRACT Suicide is a leading cause of death in the US and suicide rates have steadily increased. Despite this, there is a paucity of interventions that reduce suicide ideation and behavior. In this project, we seek to enhance a beta version of our suicide prevention digital therapeutic (developed in phase I) and conduct a randomized controlled trial to evaluate the efficacy of the digital therape ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Selective targeting of high affinity alpha4 integrins as a safe treatment strategy for IBD
SBC: Aviara Pharmaceuticals, Inc. Topic: 300Inflammatory bowel disease (IBD) is comprised mainly of Crohn’s Disease (CD) and Ulcerative Colitis (UC), and is characterized by a chronic non-resolving inflammatory response in the intestinal mucosa. Although the exact etiology is unknown, dysbiosis, genetic, environmental, and immunologic factors are all thought to play roles in this multifactorial disease. There are no cures, and in most cas ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development and Production of Standardized Reference Diets for Zebrafish Research
SBC: Meridian Biotech, LLC Topic: ODProject Summary The over-arching goal of this Phase II SBIR proposal is to optimize and implement high quality standard reference diets for the Zebrafish (Danio rerio), an animal model of critical importance to the understanding of human health and development of vertebrate organisms. A key problem in the industry is that high quality standardized reference diets, with appropriate physical propert ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Programming Metabolically Fit TILs for Immunotherapy
SBC: LIPO-IMMUNO TECH LLC Topic: NCIABSTRACT Advances in molecular biology and genetic engineering have led to the design and use of modified T cells recognize tumors to achieve significant tumor control upon adoptive cell transfer (ACT) to patients. These T cells are either transduced with tumor antigen reactive T cell receptors (TCR), or chimeric antigen receptors (CARs). Recently, a surge in studies with neo-antigen reactive T ce ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of a novel accurate therapy for multiple sclerosis
SBC: Autoimmunity Biologic Solutions, Inc. Topic: NIAIDPROJECT SUMMARYMultiple Sclerosis (MS) is the most common neurological disease of early adulthood and is mediated by autoimmune mechanisms that lead to demyelination and neuronal damage in the central nervous system, resulting in progressive neurological dysfunction. Up to date, there is no cure for this devastating disease and current available treatments focus on preventing future immunological ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDSUMMARY Arboviruses present a constant threat to human and animal health worldwide. They are transmitted by hematophagous arthropods, primarily mosquitoes. One of them, Aedes aegypti, is the primary vector of several widely spread arboviruses such as Zika, dengue and West Nile viruses, and for most of them, human-licensed vaccines do not exist or are suboptimal. These pathogens are transmitted int ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Affordable sialoglycans and associated reagents for expanded chemoenzymatic production
SBC: Integrated Micro-Chromatography Systems, Inc. Topic: 300Project Summary Sialoglycans are sialic acid-containing oligosaccharides that play important biological roles in human biology and pathology and are indispensable molecular probes for research related to bacterial and viral infection, cancer metastasis, immune regulation, etc. The multifaceted functions of sialoglycans in human milk are also being explored. Nevertheless, sialoglycan-related resear ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Improved Identification of the function of Novel and Partially Occluded Laboratory Equipment
SBC: NOVATEUR RESEARCH SOLUTIONS LLC Topic: DTRA19B002This STTR Phase II project proposes development of a statistical relational learning framework for identification of the function of laboratory equipment from imagery. The proposed framework uses semantic reasoning to incorporate evidence from multiple classifiers and feature extractors, domain knowledge, and scene context for scene understanding and labeling. The Phase II effort will focus on dev ...
STTR Phase II 2021 Department of DefenseDefense Threat Reduction Agency -
Me and You-Tech: A socio-ecological solution to teen dating violence for the digital age.
SBC: Radiant Creative Group, LLC Topic: NICHDABSTRACT The goal of this 3 year Fast-Track STTR is to develop and evaluate a multi-level (youth, parent, school) Internet-based dating violence (DV) prevention program, ‘Me andamp; You-Tech’ (MYT) for 6th--grade middle school students. By 6th grade, approximately 50% of students will have engaged in a dating relationship. Of these, almost one-third will have perpetrated physical DV and almost ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health -
Development of peptide nucleic acid antibiotics
SBC: NUBAD LLC Topic: NIAIDThe world is rapidly heading towards a pre-1940’s scenario when it comes to fighting infectious disease. Antimicrobial resistance is a growing problem on a global scale, greatly hampering our abilities to quell worldwide epidemics such as influenza, SARS, COVID-19, tuberculosis and malaria, as well as the simple staphylococcus infection. Unless innovative strategies are developed to produce robu ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health