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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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OTOREFLECTANCE ASSESSMENT OF MIDDLE-EAR FUNCTIONING
SBC: Sonicom, Inc. Topic: N/ADESCRIPTION (provided by applicant): Otoreflectance (OR) is a new class of hearing-test instruments utilizing acoustic signals presented and recorded in the ear canal. OR instruments address the following limitations in existing instruments to screen and diagnose middle-ear function: (1) detection of otitis media, (2) prediction of conductive hearing loss, (3) detection of middle-ear dysfunction i ...
STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health -
Natural feedstocks for diversity-oriented synthesis
SBC: Promiliad Biopharma Incorporated Topic: N/ADESCRIPTION (provided by applicant): This Phase II STTR application is a continuation of a previous Phase I award between the Wright group at Dartmouth College and Promiliad Biopharma. The goal of this application is to continue our efforts to develop novel chemical libraries with the diversity and complexity common to natural products as a marketable product to the pharmaceutical industry. Key to ...
STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Novel accelerated in vitro breeding for phytoremediation
SBC: SOUTHERN SUN BIOSYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): The long-term goal of the collaboration between the USC and Southern Sun BioSystems is to create a plant breeding and remediation technology-development center which would supply hardware, protocols for breeding-selection and mass production of elite plants for nurseries and remediation businesses, with licensing and tracking mechanisms for protecting intellect ...
STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Multiplex Fluorescent Dyes for Ultrasensitive Proteomics
SBC: ZDYE, LLC Topic: N/ADESCRIPTION (provided by applicant): The broad long-term goals of this project are to develop more powerful proteomics detection technology with greatly improved sensitivity, that will reveal the global patterns of biologically stimulated changes (differen tial detection) in protein levels, posttranslational modifications and enzyme activities simultaneously (using 6-12 channel multicolor fluoresc ...
STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health -
Restoration of Skin Structure and Function Post-Wounding
SBC: FirstString Research, Inc Topic: N/ADESCRIPTION (provided by applicant): The wound repair process in skin is initiated immediately after an injury and induces a cascade of events including inflammation, proliferation, and scar differentiation. The adverse changes in skin structure and function resulting from scar tissue affects over 35 million US citizens a year resulting in costs of more than 7 billion dollars). The founders of Fir ...
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Potent Antifolates as New Therapeutics for MRSA
SBC: Promiliad Biopharma Incorporated Topic: NIAIDDESCRIPTION (provided by applicant): This Phase II STTR proposal describes a collaborative effort between researchers in the Department of Pharmaceutical Sciences at the University of Connecticut and Promiliad Biopharma to develop efficacious antibiotics targeting both methicillin-resistant strains of Staphylococcus aureus (MRSA) and Streptococcus pyogenes. We have recently completed a Phase I STT ...
STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health -
Enhanced Dynamic Range Proteomic Analysis: Phase II
SBC: RESONON, INC. Topic: NCRRDESCRIPTION (provided by applicant): The long-term goal of this effort is to develop an optical module that will reduce stray light within imaging systems, thereby providing more accurate measurements from digital images and increased dynamic range of detection to enable analysis of objects not currently measurable. The present Phase II proposal is aimed at greatly enhancing the analysis of multic ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Continuous monitoring of anti-fibrinolytic therapy in cardiovascular surgery
SBC: Micro Vide, LLC Topic: NHLBIDESCRIPTION (provided by applicant): A major cause of morbidity and mortality in cardiovascular surgery is excessive bleeding post- operatively, which is commonly managed by pharmacologically modifying clot degradation (fibrinolysis), through inhibition of plasmin activity (PLact). However, the only FDA approved and most commonly used inhibitor of PLact in cardiovascular surgery, while effective i ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES
SBC: FIREFLY HEALTH INNOVATIONS NE, INC. Topic: NIDCRDESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
A Rapid assay for RNA targeted drugs: Instrumentation Supplement
SBC: NUBAD LLC Topic: 300DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health