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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Production of Chemical Reagents for Prompt-Agent-Defeat Weapons
SBC: NALAS ENGINEERING SERVICES INC Topic: DTRA14B001The US DoD requires robust ways of neutralizing threats posed by hostile powers and terrorist organizations that may be in possession of dangerous weapons of mass destruction (WMDs). Unfortunately, the weapons currently available to the DoD do not offer a way for the WMD to be destroyed without risking the spread of that material throughout the area. The strategy for the defeat of biological weapo ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency -
An Open-Source Platform for Inter-Network Analytics of High-Consequence Events
SBC: ANOMALEE INC. Topic: DTRA14B003Objectives and Intellectual Merit: The infrastructure of modern civilization is a set of complex systems1 that dynamically interact across multiple layers of abstraction. Researchers from many disciplines2 are designing analytical tools for predicting the global and local behaviors of these complicated, multi-layer networks. Easily usable, available (open source) and inter-operated tools are neede ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency -
Engineering a phosphotyrosyl-tRNA Synthetase
SBC: AXIOMX INC Topic: 300DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Measuring Bladder Permeability with MRI using a Novel Contrast Agent Formulation
SBC: Lipella Pharmaceuticals Inc. Topic: 400DESCRIPTION provided by applicant This project entails the development of a novel dual component MRI contrast agent formulation for the detecting permeability in the luminal surface of the urinary bladder The purpose of having such a test is ultimately to allow clinicians in certain circumstances to differentially diagnose a chronic non infectious inflammation of the urinary bladder from a ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Novel mass spectrometry methods for profiling modified RNA nucleotides in the nervous system
SBC: Ribonova Inc. Topic: NIDADESCRIPTION provided by applicant Pseudouridine is the most abundant post transcriptionally modified nucleoside found in ribonucleic acid RNA Pseudouridine is an enzymatically generated isomer of the canonical base uridine with additional hydrogen bonding capabilities and appears to lead to local structural and biochemical effects within RNAs Pseudouridine has been detected in several type ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Measuring toxicant effects on cellular function in a microarray format
SBC: CIENCIA INC Topic: NIEHSDESCRIPTION provided by applicant The EPA maintains a Toxics Release Inventory of over toxic chemicals that are disposed or released from more than industrial sites in the United States The Department of Health and Human Services and USDA maintain a list of over select agents and toxins that pose a severe risk to both human animal and plant health These compounds represent only ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Polaris Oncology Survivor Transition POST System
SBC: POLARIS HEALTH DIRECTIONS, INC Topic: 100DESCRIPTION provided by applicant By January oncology care providers will be expected to craft Survivorship Care Plans SCPs for all individuals ending active treatment for cancer however there is a lack of systematic study of the impact survivorship planning has on patients providers or healthcare systems The Polaris Oncology Survivorship Transition POST program is a web based sy ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
mTOR Substrate Phosphorylation: A New Bioassay for Therapeutics
SBC: COGNIZANCE BIOMARKERS, LLC Topic: 107DESCRIPTION provided by applicant There are a growing number of human diseases that have been linked to abnormally enhanced activation of the mammalian target of rapamycin mTOR signaling cascade a central pathway governing eukaryotic protein synthesis These include neurodevelopmental disorders associated with epilepsy autism and intellectual disability as well as cancer obesity and dia ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Neurotrophic Agents for Treating Parkinson's Disaese
SBC: SENEB BIOSCIENCES INC Topic: 102DESCRIPTION provided by applicant Parkinsonandapos s disease PD is a neurodegenerative disorder characterized by motor function and eventually cognitive decline GM depletion is validated as a therapeutic target for Parkinsonandapos s disease PD in clinical studies in which GM replacement stabilized motor function loss and may be disease modifying However GM has poor pharmacologic prop ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Remote Brief Intervention and Referral to Treatment Service for Alcohol (R-BIRT)
SBC: POLARIS HEALTH DIRECTIONS, INC Topic: NIAAADESCRIPTIONprovided by applicantSignificanceThe USPHSTFSAMHSACDCand NIAAA have affirmed the importance of screening in medical settings for alcohol consumption that exceeds the NIAAA low risk limitsbrief educational and motivational counseling for those who screen positive or have other evidence of an Alcohol Use Disorderandwhen appropriatereferral to treatmentSBIRTHowevertranslation to clinical p ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health