Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Biological treatment of bacterial keratitis

    SBC: AMEBAGONE, INC.            Topic: N

    DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Neuroimaging tools for presurgical brain mapping

    SBC: PRISM CLINICAL IMAGING, INC.            Topic: 102

    DESCRIPTION provided by applicant The goal of this project is to develop functional magnetic resonance imaging fMRI tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology The specific focus of this proposal is to produce a practical clinic ready suite of MR imaging methods analyses and display tools to solve the number one impediment to ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Axonal Transport HTS Platform for Neurodegeneration Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 106

    DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Restimulating memory T cell responses in elderly by a novel, live influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Respiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwide Importantly in humans the majority of morbidity and mortality following flu infection is seen in older individuals andgt year old Yet clear understanding of how aging impacts on innate immune responses and how to improve vaccine design ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Reversal of Myocardial Infarction by Localized Stimulation

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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