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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IGF OT IGF IN VITRO CANCER STEM CELL EXPANSION PROGRAM FOR RARE TUMOR TYPES PERIOD OF PERFORMANCE

    SBC: KIYATEC, LLC            Topic: NCI

    The overall objective of this proposal is to develop an in vitro process by which cancer stem cells CSC can be isolated from primary human tumor biopsies or tissues expanded without losing critical elements of stem cell qualities and then used for preclinical and clinical applications During this fast track proposal KIYATEC will employ an integrated functional and unbiased scientific strate ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. IGF OT IGF PHENOTYPIC CARDIOTOXICITY SCREENING WITH HUMAN D HEART TISSUES

    SBC: Invivosciences, Inc.            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. IGF OT IGF Development of a Novel Technology Platform for the Rapid Detection of Cell Free Methylated DNA

    SBC: Poointcare Genomics Corporation            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. IGF OT IGF RD THERAPEUTIC DELIVERY OF ADP RIBOSYLARGININE HYDROLASE SBIR TOPIC PHASE I

    SBC: PROTEIN FOUNDRY, LLC            Topic: NHLBI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Integrated biochemical and bioinformatic technologies for accurate transcriptome-wide full-length RNA assembly.

    SBC: LUCIGEN CORPORATION            Topic: 172

    DESCRIPTION provided by applicant The human transcriptome is significantly more complex than its cognate genome due to the hundreds of thousands of possible isoforms allele specific expression issues variable RNA editing changes and differential expression patterns spanning cell types developmental stages and physiological stresses Next generation sequencing NGS platforms are fundame ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Biological treatment of bacterial keratitis

    SBC: AMEBAGONE INC            Topic: N

    DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Neuroimaging tools for presurgical brain mapping

    SBC: PRISM CLINICAL IMAGING INC            Topic: 102

    DESCRIPTION provided by applicant The goal of this project is to develop functional magnetic resonance imaging fMRI tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology The specific focus of this proposal is to produce a practical clinic ready suite of MR imaging methods analyses and display tools to solve the number one impediment to ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Axonal Transport HTS Platform for Neurodegeneration Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 106

    DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. IMMEDIATE FIT USING INNOVATIVE TECHNOLOGY TRANSTIBIAL PROSTHESIS

    SBC: IFIT PROSTHETICS, LLC            Topic: NIA

    DESCRIPTION provided by applicant The goal of iFIT Prosthetics LLC r and its founder was to create and commercialize a modular immediate fit fully adjustable transtibial prosthesis system suitable for mass production using high strength polymer materials that are injection molded at a fraction of the cost of conventionally made prostheses This goal was achieved and now the aims of this P ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Aminoglycoside-Nucleic Acid Conjugates for Inactivation of an Antibiotic Resistance-Conferring Aminoglycoside Sensing Riboswitch

    SBC: NUBAD LLC            Topic: NIAID

    DESCRIPTION provided by applicant The world is rapidly heading towards a pre andapos s scenario when it comes to fighting infectious disease Antimicrobial resistance is a growing problem on a global scale greatly hampering our abilities to quell worldwide epidemics such as tuberculosis and malaria as well as the simple staphylococcus infection The proposed project is significant and has ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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