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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Validation of a salivary miRNA diagnostic test for autism spectrum disorder
SBC: Quadrant Biosciences Inc. Topic: 103Autism spectrum disorder (ASD) is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction, as well as restrictive, repetitive interests and behaviors. ASD is an increasing public health concern, with about 1 in 45 American children diagnosed with ASD in 2014, a 10-fold increase in prevalence over the past 40 years. The effect of ASD on both ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma
SBC: LEUKOGENE THERAPEUTICS INC Topic: 102Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Novel SCD1 inhibitors for treatment of cancer
SBC: MODULATION THERAPEUTICS, INC. Topic: 102Project Summary Metabolic reprogramming plays a critical role in carcinogenesisin part due its ability to promote immune suppressive properties within tumorsHoweverit is unclear whether inhibition of fatty acid metabolism in tumors affects their immunogenicityHerewe show for the first time that inhibition of stearoyl CoA desaturaseSCDthe rate limiting enzyme involved in fatty acid synthesis conver ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Clinical Translation of an Anti-Metastatic Antibody for Breast Cancer Therapy
SBC: FOR-ROBIN, INC. Topic: 102DESCRIPTION provided by applicant Translational studies are proposed to support the continued development of the JAA F antibody based therapy to address the critical need for a safe and effective treatment for metastatic breast cancer including triple negative breast cancers Building on the success of our Phase I project the overarching objectives of the Phase II application are to advanc ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Stroke Treatment by Chemically-induced Hypothermia
SBC: JT Pharmaceuticals, Inc. Topic: 101DESCRIPTION provided by applicant Stroke is a leading cause of human death and disability in the United States while clinical therapy for acute stroke is limited and unsatisfactoy The many failures in clinical trials strongly endorse the idea that to battle this multifaceted bran disorder novel strategies that target multiple cell types and different mechanisms are needed to achieve therapeut ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Noom Monitor for Binge Eating
SBC: Noom, Inc. Topic: 104DESCRIPTION provided by applicant Binge eating is a core maladaptive behavior characteristic of several forms of eating pathology including bulimia nervosa BN and binge eating disorder BED These chronic conditions affect approximately percent of the population and cause significant psychosocial and physical impairment However a number of barriers prevent the implementation of effecti ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes
SBC: Cytocybernetics Inc Topic: NHLBIProject Summary As part of the FDA approval process for novel therapeutic drugssafety screening demonstrating that the candidate drug does not have deleterious effects on the human cardiac action potential is requiredHealthy human heart cells are not available for such preclinical drug testingThere is currently no consensus on the best experimental approach to provide the most efficienteconomicala ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Calibrated Methods for Quantitative PET/CT Imaging Phase II
SBC: KITWARE INC Topic: 102DESCRIPTION provided by applicant The overall goal of this Phase II STTR proposal is to develop a PET CT imaging tool that will help accelerate the development of effective cancer therapies by improving the utility of oncology trials using PET imaging The growing cost time and complexity of clinical trials are driving patient and pharmaceutical company demand for more objective efficient a ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Microfluidic Processing of Leukocytes for Molecular Diagnostic Testing
SBC: GPB Scientific, Inc. Topic: 102DESCRIPTION provided by applicant The goal of this Phase II project is to optimize and validate a microfluidic chip based process that automates and shortens the labeling washing and collecting of human blood leukocytes WBCs for flow cytometric analysis of clinically important cell surface and intracellular markers Multi parameter flow cytometry is an increasingly powerful and widely used t ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care
SBC: Digital Health Empowerment, Inc Topic: NICHDABSTRACTAdolescents face increased HIV riskinfrequent testinginconsistent linkage to careand a lack of prevention related knowledgeWe propose to address this by completing and evaluating the Mobile Augmented ScreeningMAStool to increase youth HIV testing via a tablet based intervention in clinical settingsand then use text messages to facilitate linkage to care for those who test positiveand deliv ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health