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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Measurement of Beta Cell Death in Diabetes

    SBC: L2 DIAGNOSTICS, LLC            Topic: 200

    DESCRIPTION provided by applicant All forms of diabetes are characterized by the death of insulin producing cells In Type diabetes T D this leads to the reliance on exogenous insulin for survival Death of cells is silent it cannot be detected in vivo until it has progressed to such an extent that metabolic function is impaired The loss of cells has only been assessed by functiona ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease

    SBC: Immunext, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Systemic lupus erythematosus SLE is a devastating autoimmune disease that most commonly affects women in their child bearing years SLE attacks multiple organ systems but renal and neurologic involvement are the usual harbingers of poor outcome Despite effective albeit toxic immunosuppressive therapy only of patients with these serious manifestations ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Multivalent Lyme Disease Vaccine Targeting Tick-Host-Pathogen Interactions

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant This proposal seeks to develop a novel vaccine against Lyme disease by targeting Ixodes scapularis proteins critical for Borrelia burgdorferi transmission from the tick to mammalian host Earlier work has identified four tick proteins Salp TRE tHRF and TSLPI that facilitate different steps of spirochete transmission and immunity against these protein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. RNA Detection as an Improved Diagnostic Assay for Human Leptospirosis

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Leptospirosis a zoonotic disease is an important public health problem worldwide It is caused by spirochete bacteria belonging to nine species and more than serovars of the genus Leptospira In the US there is increasing awareness of the importance of leptospirosis as the cause of disease among inner city populations military personnel and individuals ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A Multi-Tiered Lithium-ion Battery Thermal Fault Mitigation Architecture

    SBC: CREARE LLC            Topic: N14AT006

    With the continued electrification of military systems, lithium-ion (Li-ion) batteries are increasingly targeted for electrical energy storage due to their wide operating temperature range and exceptional energy density. However, Li-ion batteries operating in hostile thermal and mechanical environments typical of military aircraft are prone to catastrophic thermally-induced failures. Hazards inclu ...

    STTR Phase I 2014 Department of DefenseNavy
  6. Seabed Imaging System

    SBC: CREARE LLC            Topic: N14AT022

    Acoustic imaging is the preferred modality for mine detection. However, acoustic images are noisy and difficult to interpret due to acoustic clutter, the interaction of sound with the seafloor, and potential penetration of sound into the sediment with subsequent reflection. Creare proposes to develop a Seabed Imaging System (SIS) capable of providing detailed information on both the topography and ...

    STTR Phase I 2014 Department of DefenseNavy
  7. Command and Control, Modeling and Simulation, Training

    SBC: SONALYSTS, INC.            Topic: MDA13T005

    The Sonalysts Team proposes to investigate, design, and develop a training system leveraging state-of-the art game and agent-based technologies with"TRILOGY,"a Modeling, Simulation, and Training (MST) system capable of three core capabilities: training, rehearsal, and analysis/CONOPS development. Sonalysts will leverage their latest commercial-off-the-shelf (COTS) game engine, Simulation Engine I ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  8. Practical Traveling Wave Parametric Amplifier for Quantum Computing and Mixed Signal Applications

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: A14AT010

    A collaboration between research engineers at Solid State Scientific Corporation and the University of MassachusettsBoston proposes the exploration of a new class of superconducting traveling wave parametric amplifier (TWPA) that exploits the large nonlinear inductance of a unique quantum device known as a superinductor. The nonlinear properties of the superinductor provide high gain of weak sign ...

    STTR Phase I 2014 Department of DefenseArmy
  9. Secure Efficient Cross-domain Protocols

    SBC: SONALYSTS, INC.            Topic: AF13AT08

    ABSTRACT: The Sonalysts team proposes to develop a solution that facilitates the flow of data between different levels of classification while improving and ensuring both security and data integrity. Our approach involves a set of protocols that provide a unique and disruptive combination of multichannel data dispersion and multi-classification data management techniques to meet our objectives. ...

    STTR Phase I 2014 Department of DefenseAir Force
  10. Advanced Infrared Focal Plane Arrays with Strained Layer Superlattice Detectors on Digital-Pixel Readout Integrated Circuits

    SBC: QmagiQ, LLC            Topic: MDA12T003

    We propose to combine QmagiQ's strained layer superlattice (SLS) sensor technology with MIT Lincoln Laboratory's novel digital pixel readout integrated circuit (DROIC) to realize an advanced longwave infrared digital focal plane array (DFPA) with high quantum efficiency, dynamic range, and operating temperature. In Phase I, we developed the basic SLS DFPA and demonstrated its extraordina ...

    STTR Phase II 2014 Department of DefenseMissile Defense Agency
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