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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. The NamesforLife Semantic Index of Phenotypic and Genotypic Data for Systems Biology

    SBC: NamesforLife, LLC            Topic: 34b

    The DOE Systems Biology Knowledgebase (KBase) was envisioned to provide a framework for modeling dynamic cellular processes of microorganisms, plants and metacommunities. The KBase will provide the tools and data to enable rapid iteration of experiments that draw on a wide variety of data and allow end-users to infer how cells and communities respond to natural or induced perturbations, and ultima ...

    STTR Phase II 2014 Department of Energy
  2. Single Step Manufacturing of Low Catalyst Loading Electrolyzer MEAs

    SBC: Proton Energy Systems, Inc.            Topic: 01a

    Proton OnSite manufactures hydrogen generation systems which can be integrated with renewable energy sources to generate hydrogen fuel while producing minimal carbon footprint. This project aims to reduce the energy required to manufacture these units through development of improved electrode application methods and reduction in platinum group metal usage.

    STTR Phase II 2014 Department of Energy
  3. An innovative in situ cell reprogramming technology for cancer treatment

    SBC: QURGEN, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): We invented an innovative protein induced Pluripotent Stem Cells (piPSCs) technology that generates piPSCs from normal fibroblast and cancer cells within 1-week with 90 4% conversion efficiency. Such high conversion efficiency enables us to pioneer an in situ cell reprogramming technology within the cancers of cancer-bearing animals. Instead of generating iPSCs ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Accurate Prostate Cancer Diagnosis for Active Surveillance Patients Using a Novel

    SBC: ProDevice Medical Supplies and Equipment LLC            Topic: NCI

    Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Removal of Amyloid-beta Peptides from the Alzheimer's Brain

    SBC: WE BIOSCIENCES, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): As the Alzheimer's disease (AD) population is growing rapidly, currently there are no cure treatments. The goal of this resubmitted STTR proposal is to conduct a preclinical study with pramlintide to prove a potential treatment for AD. We have revised the proposal significantly according to the reviewers' comments. Pramlintide is an FDA approved drug ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Novel scFv-Antibody Fusion siRNA Carrier Protein for Macroglobulinemia Treatment

    SBC: SIRNAX, Inc.            Topic: NCI

    This goal of this project is to develop an innovative process for treating patients with Waldenstr m's macroglobulinemia by suppressing the production of IgM. Waldenstr m's macroglobulinemia is incurable and fatal. The manifestations of this disease that are due to high concentrations of monoclonal IgM are hyperviscosity with headache, fatigue, impaired cognition, confusion, and stroke, ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Functional-selection of affinity reagents against DNA-protein complexes using targeted chromatin sequences

    SBC: AXIOMX INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Site-specific binding of proteins to DNA plays an important role in cell development, cell signaling, the cell cycle, and diseases such as cancer. There are two overarching goals to this proposal: (1) to develop a meansfor the identification of proteins bound to specific DNA sequences, and (2) to develop a better method for the identification of immunoprecipita ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Real-time bioimpedance based biopsy device

    SBC: RYTEK MEDICAL INC            Topic: NCI

    DESCRIPTION (provided by applicant): Over the last three decades the number of men diagnosed with prostate cancer has increased 85% as a result of new screening and diagnostic tools. However, a significant number of these newly diagnosed men are harboringclinically insignificant disease, which means that they are not likely to die from prostate cancer. A difficul decision facing urologists daily i ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Neuroprotective Agent For Cerebral Palsy Prevention

    SBC: Zietchick Research Institute, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Cerebral palsy (CP), the most common physical disability in childhood, afflicts more than 800,000 Americans and many more worldwide. In addition to motor difficulties, many children with CP also suffer from intellectualdisability, epilepsy, nutritional problems, and language dysfunction. Furthermore, almost 90% of CP-associated brain injuries occur in utero or ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Improving Asthma Control through mHealth-Based Home Monitoring

    SBC: MAD POW MEDIA SOLUTIONS, LLC            Topic: NIMHD

    DESCRIPTION (provided by applicant): Disadvantaged, urban, and minority children incur a disproportionate share of asthma prevalence and morbidity. Interventions have been shown to improve underrepresented minority (URM) youths' adherence to NIH asthma care guidelines (e.g., proper use of long-term control medication) thereby reducing asthma morbidity. One particularly promising method of int ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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