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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Additive Manufacture of Refractory Metal Propulsion Components

    SBC: GEOPLASMA LLC            Topic: T9

    Niobium alloy (C-103) reaction control system (RCS) chambers have been used on numerous NASA programs. However at elevated temperatures, the strength of C-103 decreases significantly. Higher strength niobium alloys have been developed, but these alloys lack the formability of C-103. Recently, Additive Manufacture (AM) of niobium and C-103 has been demonstrated using powder bed electron beam me ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  4. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. A device containing immobilized chelator to remove aluminum from TPN solutions

    SBC: ALKYMOS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A high percentage of the ~ 470,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common conta ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced Materials and Fabrication Techniques for the Orion Attitude Control Motor

    SBC: Plasma Processes, LLC            Topic: T901

    The Launch Abort System (LAS) for the Orion Crew Exploration Vehicle (CEV) will provide a safe escape for the crew in the event of an emergency during launch. A key component of the LAS is its Attitude Control Motor (ACM). Recent testing of the ACM valve assembly has resulted in failure during hot-fire testing. These failures are believed to be the result of the molybdenum alloy component disto ...

    STTR Phase I 2009 National Aeronautics and Space Administration
  7. Advanced Nongray Radiation Module in the LOCI Framework for Combustion CFD

    SBC: CFD RESEARCH CORPORATION            Topic: T802

    In this STTR, an innovative, efficient and high fidelity computational tool to predict radiative heat transfer will be implemented in the LOCI framework. Radiative heat transfer in rocket engine combustion can play a significant role in determining engine performance and combustor wall heat loading. Radiation will also become increasingly important as hydrocarbon-based fuels are used in rocket pro ...

    STTR Phase I 2006 National Aeronautics and Space Administration
  8. Air Vehicle Gust Response analysis for Conceptual Design

    SBC: RESEARCH IN FLIGHT LLC            Topic: T15

    Research in Flight (RIF) and Auburn University are offering the development of an advanced, robust tool and methodology that allows the simulation and modeling of gust and wake vortex encounters for Distributed Electric Propulsion (DEP) enabled Urban Air Mobility (UAM) vehicle concepts. DEP enabled UAM concepts offer the potential for large performance improvements by exploiting favorable synergie ...

    STTR Phase I 2019 National Aeronautics and Space Administration
  9. Algorithm to Identify Patients at Risk of Medication-Related Hospitalization

    SBC: L. KRENK, INC.            Topic: R

    The long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. AMD-FCRx to Restore Damaged Pigment Epithelium

    SBC: REGENEREX, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. The hallmark of the disease is retinal pigment epithelial (RPE) dysfunction with subsequent death of the foveal photoreceptors. Hematopoietic stem cells (HSC) have been demonstrated to repair damaged tissues including heart muscle and nerve under selected conditions. ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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