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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A nanoparticle delivery system for CRISPR/Cas9 based therapeutics
SBC: ATGC Inc. Topic: 100Abstract Applications of customizable nucleases such as CRISPRclustered regularly interspaced short palindromic repeatsCasCRISPR associated proteinhave enabled efficient and precise gene correction in vitroand hold promises for eventually achieving in vivo gene correction therapyHoweverto apply CRISPR Casin therapeutic settingsseveral major challenges remain to be addressedihomologous recombinatio ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A software tool for objective identification of concussion-related vision disorders using a novel eye-tracking device
SBC: Oculogica Inc. Topic: 102ABSTRACT This project will create the first objective measurement toolthe VisBoxfor the vision subtype of concussionVSCThis will enable physicians to identify VSC without an eye care professionalfor referral to a vision specialist for personalized vision therapy recommendationsThe persistence of concussion symptoms beyond several weeks is often a life altering situation for affected individualsand ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Automated Assessment of Leptomeningeal Collaterals on CT Angiograms
SBC: KITWARE INC Topic: 108AbstractThe primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiographyCTAas a quantitative assessment of acute ischemic strokeLeptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal vessel occlusionThe presence and effectiveness of leptomeningeal collateralsi ecollateral statusvaries significant ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Bitter Human Taste Bud Epithelial Cell Platforms for Bitter Taste Antagonist Discovery
SBC: DISCOVERYBIOMED, INC. Topic: NIDCDPrincipal Investigators for Small BusinessDiscoveryBioMedIncDBMand Monell Chemical Senses Center Project Summary Abstract Bitter taste in foods and medicines presents a barrier to overcoming global public health challengesfood insecuritypoor nutritional healthand poor compliance with medication useparticularly among children and the elderlySugar and saltthe mainstays to address these challengesfur ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Commercialization of a Rapid Blood Test for Traumatic Brain Injury
SBC: Fawkes Biotechnology, LLC Topic: 100Traumatic brain injuryTBIis a substantial health care issue affecting both civilian and military populationsAlthough extremes of head injury are recognizablemild to moderate TBImmTBIis more difficult to diagnose leading to a need for the identification of circulating biomarkers of brain injury that may facilitate early identificationUsing a rat model of TBI we identified a novel marker of neuronal ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development and Validation of a Physical Anatomic Model for Surgical TrainingUsing 3D Printing Technology
SBC: Simulated Inanimate Models LLC Topic: NIBIBProject SummarySimulation training is unique in its ability for repetitive practice of a wide variety of scenarios and to reflect on performance without jeopardizing a patient s safetyMedical simulation provides a controlled setting with step wise skills progressionutilizing continuous feedback and assessment aiming at the ultimate goal of skills transfer to clinical competenceSurgical skills simu ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of Drug Delivery Technology for Stem Cell-Based TMJ Regeneration
SBC: WNT SCIENTIFIC LLC Topic: NIDCRSummary The temporomandibular jointTMJis a complex joint system critical for dentalocclusionmasticationrespiration and speechThe TMJ is comprised of a network of musclesligamentsand a fibrocartilaginous disc and condyleTMJ trauma and degenerative diseasesincluding TMJ osteoarthritisOAare debilitating and compromise quality of lifeTMJ diseasesafflict overmillion Americans at an annual cost of$billi ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of KLS-13019 for Chemotherapy Induced Peripheral Neuropathy and Drug Dependence
SBC: KannaLife Sciences Inc. Topic: NIDAChemotherapy induced peripheral neuropathyCIPNcan be a chronicseverely debilitating consequence of cancer therapy for which there are no effective management strategiesMoreoverupwards ofof CIPN patients reported using prescription opioids for pain management despite the fact that there is only weak evidence that long term continuation of opioids provides clinically significant pain relief in these ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Dressing Assistant: Home Technology to Sustain Independent Dressing in Dementia
SBC: INVENTORS WORKSHOPS INC Topic: NIAAbstractPersons living with dementiaPWDoften require assistance with routine activities and daily tasksWorkloads placed on caregivers often results in high levels of physical and emotional stressand depressionand higher overall morbidity and mortality ratesFocus group of caregivers for individuals with mild to moderate dementiaidentified dressing the PWD as the most pressing and stressful daily co ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes
SBC: Cytocybernetics Inc Topic: NHLBIProject Summary As part of the FDA approval process for novel therapeutic drugssafety screening demonstrating that the candidate drug does not have deleterious effects on the human cardiac action potential is requiredHealthy human heart cells are not available for such preclinical drug testingThere is currently no consensus on the best experimental approach to provide the most efficienteconomicala ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health