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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Pigment Sensing Pulse Oximeter Technology for Mitigating Racial Bias in Oxygen Saturation Measurements

    SBC: PENDERIA TECHNOLOGIES, INC.            Topic: 100

    Abstract Wearable pulse oximetry sensors are among the most ubiquitous medical technologies used in healthcare. Clinicians rely on pulse oximeters to monitor patient health during disease states and medical procedures. However, numerous studies have shown this technology to be racially biased; hypoxemia is three times more likely to go undetected in patients with dark skin compared to those with l ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Development of an Orally Available Therapeutic for Neutralizing C. difficile Toxin B

    SBC: NECTAGEN INC            Topic: NIAID

    Infection with the bacterium C. difficile is the most common and increasingly prevalent cause of diarrhea. In the United States, cases of C. difficile infection (CDI) are estimated to number 500,000 annually and to result in an estimated 15,000 to 30,000 deaths. The cost of these cases is thought to exceed $4.8 billion annually. CDI continues to cause discomfort, serious illness and sometimes deat ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Making Mindfulness-Based Cognitive Therapy accessible for underserved pregnant people: Developing Center M for commercialization

    SBC: CENTER MOM, INC.            Topic: 104

    PROJECT SUMMARY/ABSTRACT A highly effective intervention to prevent perinatal depression, mindfulness-based cognitive therapy for perinatal depression (MBCT), exists; however, critical implementation gaps prevent its wide use. And though universally recommended, not all prenatal care clinics effectively screen for perinatal depression (PD). Overcoming current implementation gaps is imperative to a ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Antisense Oligonucleotides to Regulate Gamma' Fibrinogen Levels

    SBC: Gamma Therapeutics, Inc.            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT g' (pronounced "gamma prime") fibrinogen (GPF) is an alternative splice isoform of the blood coagulation factor fibrinogen. This fibrinogen variant contains a high affinity binding site for the coagulation factor thrombin that localizes thrombin on the growing blood clot. Thrombin binds to GPF via thrombin's heparin binding site. This allows thrombin to continue forming th ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. An adjustable stiffness orthosis to maintain muscle engagement and push-off power in cerebral palsy.

    SBC: BIOMOTUM, INC.            Topic: NICHD

    PROJECT SUMMARY/ABSTRACT Ankle foot orthoses (AFOs) are commonly prescribed to improve mobility for individuals with neurological disorders. AFOs are included in the standard of care for the majority of ambulatory children with cerebral palsy (CP), a pediatric-onset movement disorder caused by insult to the developing brain. Current goals of treatment for individuals with CP center around increasi ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Aim protein-based anti-inflammatory therapeutic for the treatment of IBD

    SBC: Keybiome LLC            Topic: 300

    Inflammatory bowel disease (IBD), which is subdivided into ulcerative colitis (UC) and Crohn’s disease (CD), constitutes a prevalent and growing clinical health problem worldwide. These diseases are characterized by debilitating symptoms including diarrhea, abdominal pain, and fatigue, and increased risk of gastrointestinal cancers. In addition, IBD patients have perturbed intestinal microbiomes ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. STARTUP Central

    SBC: CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC            Topic: 500

    PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Practice Wellness: Equipping home visitors with skills in reflective coaching, parent mediated child development, and occupational wellness to strengthen child outcomes among low-resourced families

    SBC: SAAVSUS INC            Topic: NICHD

    The first 3 years of a child’s life are critical in setting the stage for future learning, behavior, and health. Children living in poverty during these formative years are exposed to environments characterized by insufficient human service resources and greater exposure to multiple forms and frequency of adverse events, which can undermine their developmental potential. Home visiting has become ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. GPR39 as a Therapeutic Target in Subarachnoid Hemorrhage (SAH)

    SBC: NeuvaRx, LLC            Topic: 106

    TITLE: GPR39 as a Therapeutic Target in Subarachnoid Hemorrhage (SAH) Summary Abstract Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke that affects 20-30,000 patients in the US every year, killing between a third and a half of its victims. Worldwide, SAH is responsible for more than 400,000 deaths each year. There is currently no effective treatment for SAH beyond the init ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Development of an improved intranasal vaccine against influenza

    SBC: NAJIT TECHNOLOGIES INC            Topic: NIAID

    Despite the development of several types of influenza vaccines (live-attenuated, inactivated, subunit), the World Health Organization estimates that seasonal influenza is still responsible for 3-5 million cases of severe disease and 290,000-650,000 deaths each year. Although vaccination programs have helped to reduce the morbidity and mortality associated with seasonal influenza, current vaccine a ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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