Award Data

DESCRIPTION (provided by applicant): The ultimate objective of this proposed program is the commercialization of a neonate ventricular assist device (VAD). Although VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in small infan ...

DESCRIPTION (provided by applicant): This Phase I proposal seeks support to evaluate the feasibility of developing an extracellular matrix (ECM) biologic scaffold as a repair device for atrial septal defects (ASD). ASDs are one of the most common forms of congenital heart disease and account for approximately 30-40% of all congenital heart defects seen in adults. Closure of an ASD can be performed ...

DESCRIPTION (provided by applicant): The ability to culture human embryonic stem cells generated a great deal of excitement about their vast potential for treating a variety of human diseases such as diabetes, heart disease, neurological, retinal and skin disorders to name a few. Unlike adult stem cells, embryonic stem cells have indefinite growth potential and the potential to develop into any t ...

Advanced Diamond Solutions, Inc. proposes the development of a novel high efficiency solar cell design based on amorphous diamond nanotip thermoelectric power generation properties. Amorphous diamond has a unique set of material characteristics stemming from its combination of graphitic, diamond and carbon-nanotube structures. Amorphous diamond inherently possesses numerous discrete energy state ...

Advanced Membrane Systems Inc. (AMS) proposes a 6-month research effort to demonstrate the feasibility of producing a separator for BA-5590 primary batteries. It is proposed to modify the formulation and process condition of an existing separator developed by AMS for lithium ion cells and make it more porous and suitable for BA-5590 batteries and deliver separator samples to DoD labs and battery m ...

The objective of this project is to develop and validate a CAD tool for the rapid design of mechanically fastened repairs, bonded repairs, and hybrid repairs involving both adhesive bonding and mechanical fasteners. To allow use by non-specialists, the CAD tool will replace the current process of manual construction of joint finite element models with CAD tinker toy assembly using parametric par ...

DESCRIPTION (provided by applicant): Pancreatic adenocarcinoma is the fourth leading cause of cancer deaths in the US; with less than one-year median survival, it accounts for approximately 30,000 diagnoses and deaths per year. Multimodality therapy, including surgery, radiation and chemotherapy, have not made a significant impact on the outcome and serve mostly as palliation. Thus, new treatment ...

Infrared sensors play an important role in missile defense systems, and continued improvement in their performance is critical as adversary payloads become smaller, cooler, and dimmer. While there can be no substitute for in-situ performance testing, the risks, cost, and development time for future systems can be reduced through accurate scene and sensor simulations. Current scene simulation alg ...

This effort to nowcast and forecast the Battlespace environment will predict the real world occurrence and structure of stressing atmospheric phenomena by developing a prototype tool and operational concept that demonstrate forecasting capability and accuracy improvements. Our approach to this problem involves locating and identifying stressing optical backgrounds contained in measurements and ex ...

The two primary motivations for this work are: First, to provide forecasts of dispersion of a hazardous release and associated uncertainty (or “error bars”) based on the available ensemble MET data. Second, to provide an efficient and user-friendly tool for decision makers supporting both deterministic and ensemble forecast MET data as well as resulting dispersion model forecasts. To achieve ...