Award Data

We propose to develop a computer based system for the online analysis of bio-behavioral signals associated with momentary loss of alertness. We will continue our development of bio-behavioral measures indicative of lapses in alertness. Our system will use only measures that can be obtained without attaching sensors to the operator. We will concentrate on monitoring the oculomotor system using came ...

DESCRIPTION (provided by applicant): Highly multiplexed detection of biological molecules and their activities has been an essential element of modern molecular diagnosis, drug development and research in genomics and proteomics. Well established DNA array methodologies exist which permit highly multiplexed detection of transcripts. Similar methodologies for detecting or measuring activities of pr ...

The objective of this proposal is to further explore PbSnSe detector array on Si substrate. Two approaches are proposed. One is a zero-risk incremental advance that employs a new growth condition to reduce the dislocation density. Another approach is a novel fabrication technique with high-risk but it could enable revolutionary rather than evolutionary advances. IV-VI semiconductors such as Pb1-x ...

"The future battlefield will feature highly advanced targeting and firepower and will therefore require significant advancements in real-time information feed back for individual soldiers. Advanced communications and sensors systems can inform the soldierand his commander of, for example, the locations and identities of hazards and details of his physical condition. To advance this goal, radio-f ...

"The proposed Phase 2 program focuses on the development of Powered Resonance Tube (PRT) actuators for application to Active Flow Control (AFC). For effective control across the full operating envelope of an air vehicle, high bandwidth and authority arerequired. In Phase 1, a new variable-frequency PRT actuator concept was developed and its feasibility was demonstrated. In Phase 2, the new actu ...

"Flight demonstration of modern stealthy aircraft with an active flow control system is an important, complex, and challenging opportunity. The probability of success is maximized by a progressive plan in which complexity is introduced gradually. Wepropose a plan that includes flight testing of a simple system in Phase I and progressing to a multi-axis demonstration in Phase II. The proposed pr ...

"A system that integrates the use of zero frequency and high frequency flow control is proposed to reduce aero-optic distortions by minimizing large-scale shear layer structures. An important measure of performance for a tactical laser system is theintensity of the beam on a target. The performance of these systems is degraded by index of refraction variations introduced by large-scale flow stru ...

In this Phase I STTR, Nomadics has teamed with the Keck Graduate Institute to develop a new form of highly sensitive biological filter intended for the protection of water supplies. In light of the growing concern about bioterrorism, an early warningsystem for the presence of biological agents in potable water would be desirable. The proposed system will be capable of supplying real-time data in ...

Nomadics has teamed with the University of Rhode Island to propose a sensor payload to be carried by a REMUS unmanned underwater vehicle in order to patrol coastal regions and the areas around deployed ships for protection against attack. The system willbe able to patrol large areas autonomously and detect threats from radiological, chemical, and biological weapons of mass destruction. Further, ...

DESCRIPTION (provided by applicant): The goal of the project is to develop new positive inotropes, represented by specifically modified AMP molecules. All of the currently available positive inotropic agents have significant adverse effects with digitalis being the only orally available positive inotrope. ATP causes a pronounced positive inotropic effect. Receptors for ATP, known as P2 purinergic ...