Award Data

ABSTRACT: MO-SCI Corporation and Missouri University of Science and Technology have developed and evaluated fusion welding technology applicable to ultra-high temperature ceramic (UHTC) composite joining during a Phase I ceramic joining program. This Phase II program will improve arc and reactive plasma arc welding techniques and consumables to improve joint quality. Work in the Phase I resulted ...

ABSTRACT: The objective of the Phase II effort is to extend the mathematical model investigated in the Phase I to include wind speed as well as temperature modeling, continue its development for a University of Notre Dame Wind Tunnel Facility, and demonstrate utility by adopting the model to a government facility specified by AFOSR. Specifically, the Phase II will include developmental work in ma ...

ABSTRACT: The proposal outlines work and time tables associated with finalizing the development of wear model concepts developed in Phase I work to predict the wear of two materials sliding with respect to each other while being subjected to high velocities and/or high pressures. In parallel with this, a severe wear bench test fixture design will be finalized, built, and utilized to validate the ...

DESCRIPTION (provided by applicant): Sudden cardiac death is a major cause of death around the world, with approximately 400,000 sudden deaths per year in the United States, more than are attributed to lung cancer, breast cancer, or AIDS. It is often caused by ventricular fibrillation (VF) and ventricular tachycardia (VT). VF is the most frequent mechanism of sudden death. Implantable cardiac defi ...

DESCRIPTION (provided by applicant): Pulmonary fibrosis, a group of incurable lung diseases with high mortality rates, is characterized by inflammatory cell infiltration, fibroblast proliferation, and excessive deposition of extracellular matrix proteins in lung parenchyma. Globally, five million people are affected by pulmonary fibrosis. In the U.S. alone, 200,000 suffer from this disease. Of the ...

DESCRIPTION (provided by applicant): Databases of biological sequences have proven valuable for understanding the organization of human and other genomes, for unraveling the etiology of genetic disorders, and for studying medically important pathogens. Unfortunately, these databases are growing at an exponential rate, posing a severe problem for bio-sequence annotation. Specialized hardware implem ...

Establishing the reliability of embedded software-based systems is increasingly important as the DoD's dependency on software grows and the size and complexity of software systems increase. Currently, no theory is in general practice that adequately explains the behavior of software systems reliability in a consistent and repeatable way. Currently, we cannot point to a best practice (although Jo ...

Mo-Sci Corporation and the University of Missouri-Rolla (UMR) propose to develop novel high-strength and optically transparent glass fiber reinforced polymer matrix composites as light-weight structural components, by layering and processing a polymer matrix reinforced with glass ribbons (micron-size glass fibers with rectangular cross section) of matching refractive index. The objective of this p ...

DESCRIPTION (provided by applicant): Detection of the presence and the determination of the amount of a specific protein using various techniques utilizing antibodies specific to the target protein are one of the most important tools in biomedical research, medical diagnosis and detection of biological threat agents. These techniques (such as, for example, ELISA) take advantage of the exquisite sp ...

DESCRIPTION (provided by applicant): Diabetes mellitus and related metabolic syndrome represent perhaps the fastest growing major disease market in the developing world. Diabetes has recently been described as "a global pandemic" that affects nearly 200 million people worldwide and costs this country more than $130 billion. Diabetes is a chronic disease characterized by a series of metabolic defec ...