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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Advanced Mechanical Testing System for Highly Irradiated Materials

    SBC: Product Innovation And Engineering, LLC            Topic: 32a

    This project will research and develop an Advanced Mechanical Test (AMT) system to perform comprehensive, high throughput, automatic mechanical characterization using miniature tensile specimens for highly irradiated materials. The solution should aid in a dramatic reduction of irradiated material waste, remote operation within hot cell environments, and stochastic characterization. It can also be ...

    STTR Phase II 2019 Department of Energy
  2. Development of Flow-Pattern Manipulator for Membraneless Seawater Desalination

    SBC: ThermoFlow Labs, LLC            Topic: 21a

    By 2025, 1.8 billion people will be living in places with severe water scarcity and two-thirds of the global population will encounter some degree of water stress. If warming continues at the current pace, by 2030 half of the world’s population will experience severe water stress (Runte 2016). The demands are strong; the restraints, on the other hand, come from (1) high capital investment for eq ...

    STTR Phase I 2018 Department of Energy
  3. Advanced Mechanical Testing (AMT) System for Highly Irradiated Materials

    SBC: Product Innovation And Engineering, LLC            Topic: 32a

    Establish means and methods to perform comprehensive mechanical characterization using miniature tensile specimens for highly irradiated materials. The solution should aid in dramatic reduction of irradiated material waste and provide feasibility for easy incorporation and remote operation within hot cell environments. Based on previous research, an Advanced Mechanical Test (AMT) test bed incorpor ...

    STTR Phase I 2018 Department of Energy
  4. Towards a New Generation of Glycoengineered Pneumococcal Bioconjugate Vaccines

    SBC: VaxNewMO            Topic: NIAID

    PROJECT SUMMARY Pneumococcal pneumonia remains the leading cause of bacterial pneumonia in both children under years of age and adults over years of age The standard preventative therapy is the conjugate vaccine Prevnar which consists of an immunogenic carrier protein covalently attached to one of thirteen pneumococcal capsular polysaccharides Although Prevnar has significantly red ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. ErythroMer Nanoscale Bio Synthetic Red Cell Substitute

    SBC: Kalocyte Inc            Topic: NHLBI

    PROJECT SUMMARY There is need for an artificial oxygen O carrier to substitute for banked blood in settings where stored blood is unavailable pre hospital care transport austere environments undeveloped countries or undesirable transfusion risk exceeds benefit To address this need we developed ErythroMer EM a first in class nano cyte blood substitute EM is a deformable ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Develop a new cisplatin based drug combination with reduced ototoxicity

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: NIDCD

    PROJECT SUMMARY In spite of recent new drug developments platinum based drugs such as cisplatin are still widely used to treat solid organ malignancies Besides its limited efficacy serious side effects have been associated with the use of cisplatin such as bilateral and irreversible hearing loss In the cochlea cisplatin can trigger the production of reactive oxygen species and activate sev ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a Nutraceutical Product against Noise Induce Hearing Loss

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: NIDCD

    PROJECT SUMMARY The most common occupational and environmental hazard in this country is noise Itandapos s not surprising then that noise induced hearing loss NIHL is the second most common form of sensorineural hearing deficit behind only age related hearing loss presbycusis Although therapeutics that target the free radical pathway have shown promise for reducing NIHL there are no effe ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Fibrin Specific Nuclear Probe to Reduce LVAD Adverse Events

    SBC: CAPELLA IMAGING, LLC            Topic: NHLBI

    Despite the myriad major advances in cardiology the prognosis for patients with severe medically refractive heart failure HF is exceedingly poor Approximately deaths occur annually in patients with HF who have endured an impaired quality of life often accompanied by significant economic and personal losses due to recurrent hospitalizations At least of these deaths were directl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. New Assays for Expression Profiling of MicroRNAs

    SBC: Nawgen, LLC            Topic: 172

    DESCRIPTION provided by applicant MicroRNAs miRNAs are involved in many diverse biological processes and a single miRNA can modulate the expression of hundreds of gene targets Changes in miRNA expression could have profound biological impacts leading to a variety of human diseases To date most miRNA expression profiling studies have relied on microarrays or high throughput RNA sequencing ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Cost-Effective YSZ Coating Methods for SOFC Interconnects

    SBC: MO-SCI Corp.            Topic: 14b

    Solid oxide fuel cells (SOFCs) require robust seals that can prevent intermixing of air and fuel, remain inert in reducing and oxidizing environments while in contact with SOFC materials, and maintain their effectiveness through repeated thermal cycles. Recent research has focused on compliant (or viscous) glasses that remain vitreous over time in the SOFC stack operating environment, and are able ...

    STTR Phase I 2014 Department of Energy

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