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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improved Outcome Prediction In Galactosemic Newborns

    SBC: ADVANCED BREATH DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic children with a broad spectrum of mutations in the human GALT gene that codes for galactose-l-phosph ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Improved Outcome Prediction In Galactosemic Newborns

    SBC: ADVANCED BREATH DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic children with a broad spectrum of mutations in the human GALT gene that codes for galactose-l-phosph ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Microcontact printer for ophthalmic tissue engineering

    SBC: ALCES Technology, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will demonstrate a prototype microcontact printing aligner for use in ophthalmic tissue engineering. The performance of the microcontact printing aligner will be refined and validated by experiments conducted in collaboration with the Stanford Ophthalmic Tissue Engineering Laboratory. Functioning much like traditional rubber-stamping methods, micro ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Construction of a Respiratory Syncytial Virus Replicon

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the most important respiratory pathogen in infants, especially those born prematurely. It is also an important cause of disease in the elderly and immunosuppressed. There is no vaccine available to protect against RSV and "at risk" infants are presently treated by passive immunization. An effective small molecule drug that ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Multiplexed Gene Assays by Microtiter Plate Microarrays

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The drug discovery industry is under increasing pressure to rapidly prioritize compound candidates based on their efficacy and specificity. Although traditional chip based gene expression microarrays can provide significant insights, sample format and throughput considerations preclude more widespread use. Microtiter plate based microarray (MPMA) systems can be ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Gene Expression and Diagnosis of Autoimmune Disease

    SBC: ARTHROCHIP, LLC            Topic: N/A

    DESCRIPTION (provided by the applicant): Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes, and multiple sclerosis, are thought to arise from abnormalities of innate or adaptive immune responses. Autoimmune diseases are often difficult to diagnose, as the symptoms can be typical of other conditions and quite vague, such as musculoskeletal complaints ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Gene Expression and Diagnosis of Diabetes

    SBC: ARTHROCHIP, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Autoimmune diseases are difficult to diagnose, as the symptoms can be typical of other conditions and quite vague. No currently available blood test accurately excludes or includes the possibility of an autoimmune disease in a subject, and a battery of tests and a period of observation are usually required. A single test that could readily distinguish between ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Eradicating Biofilms with Atmospheric Glow Plasma

    SBC: Atmospheric Glow Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which cause serious problems on medical and dental instruments and devices. The use of atmospheric plasma to ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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