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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. ANTIVIRAL SCREENING AGAINST MULTIPLE VIRUSES

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (Provided by applicant): Although cell-based screening has been used successfully throughout the drug-discovery field, it is problematic when screening for antiviral compounds. This is because it requires inoculation of infectious virus onto the cells and the production of additional infectious progeny virus. Handling such infectious material is not easi ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  2. INDICATOR CELLS FOR ANTIVIRAL SCREENING FOR FILOVIRUSES

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop the commercial potential of a cell-based assay to screen for compounds with antiviral activity against filoviruses such as Ebola and Marburg viruses. The basis of this bioassay, which has been prototyped with respiratory syncytial virus, is infection-independent expression of a reporter gene from an artificial viral genom ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  3. ANTIVIRAL SCREENING ASSAYS BASED ON HCV REPLICONS

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (Provided by applicant): Hepatitis C virus (HCV) is the most prevalent chronic blood-borne infection in the U.S and a global health problem. Approximately 4 million individuals in the U.S. and 170 million individuals worldwide are chronically infected. As much as 40 percent of chronic liver disease is HCV related and this results in up to 10,000 deaths each year. Despite improvements, ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  4. ANTIVIRAL SCREENING ASSAYS BASED ON HCV REPLICONS

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (Provided by applicant): Hepatitis C virus (HCV) is the most prevalent chronic blood-borne infection in the U.S and a global health problem. Approximately 4 million individuals in the U.S. and 170 million individuals worldwide are chronically infected. As much as 40 percent of chronic liver disease is HCV related and this results in up to 10,000 deaths each year. Despite improvements, ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  5. LOW RISK ILLICIT DRUG LEVEL MONITORING

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to develop two prototype drug analyzers interfaced with automated analysis readers for low risk monitoring of illicit drug levels by Surface Enhanced Raman Immuno Assay (SERIA). The first prototype will be placed in a clinical setting. This study will include urine and saliva samples collected from clients of a juvenile ass ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  6. LOW RISK ILLICIT DRUG LEVEL MONITORING

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to develop two prototype drug analyzers interfaced with automated analysis readers for low risk monitoring of illicit drug levels by Surface Enhanced Raman Immuno Assay (SERIA). The first prototype will be placed in a clinical setting. This study will include urine and saliva samples collected from clients of a juvenile ass ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. RAPID DETECTION OF MULTIPLE BIOTERRORISM AGENTS

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The long terms goal of this research is the development of a portable instrument that will allow a relatively untrained operator to determine the presence and amount of up to twenty bioterrorism agents in a matter of fifteen to twenty minutes. The assay will be simple and very nearly immune to operator error. The principle application of the device will be for ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  8. MICROWAVE TECHNOLOGY FOR SUPERFUND SITE REMEDIATION

    SBC: CHA CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): CHA Corporation has developed a microwave-based air purification technology that can be effectively utilized to recover chemicals from soil vapors produced during hazardous site remediation without using a catalytic oxidizer. A field-ready prototype microwave treatment system will be designed, constructed, and tested in the laboratory during the first year of ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  9. TARGET VALIDATION METHODS FOR NEMATODE CONTROL AGENTS

    SBC: Divergence, Inc.            Topic: N/A

    Infections by roundworm parasites, called nematodes, result in human mortality and morbidity, especially in subtropical and tropical regions of Africa, Asia, and the Americas. The World Health Organization estimates 2.9 billion people are infected. There are 595 known nematode parasites of vertebrates including hundreds that infect domesticated animals. Widespread use of drugs to control parasites ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  10. TARGET VALIDATION METHODS FOR NEMATODE CONTROL AGENTS

    SBC: Divergence, Inc.            Topic: N/A

    Infections by roundworm parasites, called nematodes, result in human mortality and morbidity, especially in subtropical and tropical regions of Africa, Asia, and the Americas. The World Health Organization estimates 2.9 billion people are infected. There are 595 known nematode parasites of vertebrates including hundreds that infect domesticated animals. Widespread use of drugs to control parasites ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
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