Award Data

DESCRIPTION (provided by applicant): Alcohol misuse continues to be a major public health problem in the United States, contributing substantially to morbidity, mortality, and social costs. There is a solid body of evidence supporting screening and brief intervention (SBI) for alcohol misuse on both public health and cost-effectiveness grounds, and the practice is endorsed by the U.S. Preventive H ...

DESCRIPTION (provided by applicant): Effective early intervention depends on reliable identification of risk for communication impairments as soon as possible. Established infant risk factors for communication impairments include poor turntaking, gestures,receptive language, commenting, symbolic play, and speech. Although these risk factors can be detected by 12- 18 mos. and reliably predict later ...

DESCRIPTION (provided by applicant): The objective of our grant application is to develop an in vitro model of the blood-brain barrier and assays to examine permeability by using isolated brain microvessels. Unlike capillaries in other organs, brain capillaries establish a barrier that is largely impermeable to polar and larger chemicals, which are due to tight junctions, the absence of both f ...

DESCRIPTION (provided by applicant): Safe and reliable access to major blood vessels and internal organs will be beneficial to patients with cardiovascular disease and cancer. An interventional catheter with ultrasound imaging capability will be developedto enable image-guided access to blood vessels and internal organs. Computer simulations and preliminary data using a transducer similar to that ...

DESCRIPTION (provided by applicant): Anxiety disorders are the most common psychiatric disorders among youth, with lifetime prevalence ranging between 18-20% of the general population. Among anxiety disorders, social phobia (SP) affects 8% of all youth, resulting in significant short and long-term impairment, including increased likelihood of substance abuse, limited academic achievement, attenuat ...

DESCRIPTION (provided by applicant): Today's cardiac imaging field requires diagnosticians to master an ever-expanding knowledge base (KB) while the time to master this knowledge, apply it to specific tasks and reimbursement are steadily shrinking. These constraints pose a serious healthcare problem that inevitably leads to physician's errors. Thus new tools are required to assist physic ...

DESCRIPTION (provided by applicant): The prevalence of overweight and obesity in children is very high and the incidence is increasing, especially among ethnic minority children. Obesity in childhood is associated with a high risk of continued obesity intoadolescence and adulthood. This is of great public health significance because obesity increases risk for the development of type 2 diabetes and ...

DESCRIPTION (provided by applicant): MicroFlex Technology for Early Detection of Lung Cancer Project Summary MicroFlex technology will provide unprecedented flexibility and controllability for bronchoscopes, enabling minimally invasive bronchoscopy to reach previously inaccessible peripheral bronchi and provide direct visualization and tool manipulation capabilities for diagnostic and therapeutic ...

DESCRIPTION (provided by applicant): This Phase II proposal integrates emerging technologies to expand the behavioral health capabilities and technological sophistication of the Journey to Disaster RecoveryTM website. This web-based system is designed to help restore a sense of control (i.e. coping efficacy) and mastery to survivors by providing a) knowledge to assist in understanding the recovery ...

DESCRIPTION (provided by applicant): This application represents a competing renewal request for a Phase II STTR project, in which we constructed an ultra-fast gradient system for magnetic resonance imaging. Operation of the novel system is based upon theprinciple that the nervous system is relatively insensitive to very short exposures to changing magnetic fields. As a result, we are showing in c ...