Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to provide the refrigerant industry with the first commercial designs for separating complex, multi-component, azeotropic refrigerant mixtures for economical recycling. The American Innovation and Manufacturing Act authorizes the Environmental Protection Agency (EPA) to phase down prod ...

The broader impact of this Small Business Technology Transfer (STTR) Phase II project involves continued development of technology to extend the therapeutic window of cell-based tissue regeneration therapies. This technology could significantly enhance the scientific understanding of cellular therapies and enable the healing of injuries more rapidly and less invasively than current techniques. A s ...

Project Summary / Abstract Chemotherapy induced peripheral neuropathy (CIPN) is a major side effect of oxaliplatin, a key drug in 1st line regimens for treating colorectal cancer. Dose-limiting CIPN prevents rt25% of patients from receiving full, maximally effective dose of oxaliplatin. In addition, 10-40% of patients receiving oxaliplatin-based therapy for colorectal cancer with develop chronic C ...

Infection with the bacterium C. difficile is the most common and increasingly prevalent cause of diarrhea. In the United States, cases of C. difficile infection (CDI) are estimated to number 500,000 annually and to result in an estimated 15,000 to 30,000 deaths. The cost of these cases is thought to exceed $4.8 billion annually. CDI continues to cause discomfort, serious illness and sometimes deat ...

PROJECT SUMMARYLoss of functional mobility associated with aging is the leading cause of dangerous falls and loss of living independence. Approximately 60% of community-residing individuals rt80 years-old have a gait disorder, and abnormal gait patterns are associated with a greater than two-fold increased risk of institutionalization and death in comparison to age-related adults without gait impa ...

Age-related hearing loss (ARHL) is the predominant neurodegenerative disease of aging. Recent animal studies have demonstrated that the earliest cochlear pathology due to noise and aging involves a loss of the inner hair cell ribbon synapse. The early consequences of this synaptic loss are not believed to affect hearing sensitivity, but rather, impair speech understanding in background noise. Whil ...

PROJECT SUMMARY Sarya LLC (Sarya) is a nuclear medicine technology company formed to commercialize radiopharmaceuticals. The goal of this Fast-Track STTR is to develop a new specific imaging agent for diagnosis, staging, and treatment of the hematological cancer, multiple myeloma (MM). MM is the 2nd most common blood cancer with an estimated 32,000 new cases and 13,000 deaths per year. Accurate de ...

PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable next-generation lithium battery technologies that are integral in transitioning toward increased renewable energy deployment. In particular, the project has the potential to overcome obstacles to widespread electric vehicle (EV) adoption including battery capacity limitations, hig ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will be to reduce the risk of complications and associated costs caused by standard bag valve mask (BVM) resuscitators, which are widely used in emergency resuscitation and airway management. In the United States, about 13.1 million BVMs are used annually. Medical providers frequently deliver ...