Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Innovative Mitigation of Radiation Effects in Advanced Technology Nodes

    SBC: Microelectronics Research Development Corporation            Topic: DTRA16A003

    Micro-RDC has developed portable radiation effects test structures that scale to new process nodes.These structures will enable the investigation of the effects of radiation on the new technology from the material processing level as well as the circuit level.Fabricating the chosen structures and the refinement of software to extract the model parameters will be completed in this effort.A suite of ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  2. Development of Fibrin-Specific Nuclear Probe to Reduce LVAD Adverse Events

    SBC: CAPELLA IMAGING, LLC            Topic: NHLBI

    Despite the myriad major advances in cardiologythe prognosis for patients with severemedically refractive heart failureHFis exceedingly poorApproximatelydeaths occur annually in patients with HF who have endured an impaired quality of life often accompanied by significant economic and personal losses due to recurrent hospitalizationsAt leastof these deaths were directly related to severe heart fai ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Cuff Electrodes with Soft Wire Electrical Leads

    SBC: TDA Research, Inc.            Topic: 102

    Project Summary AbstractDevelopment of a Nerve Cuff Electrode from Soft and Elastomeric Conducting Wires STTR Phase I ApplicationPIBrady ClapsaddleTDA ResearchIncBio electronic interfaces are used in a wide array of applications for recording and providing electrical impulses to treat diseaseOne common interface device for the PNS is the cuff electrodeCurrent cuff electrodes have many failure mode ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Smart Sensor Bandage for Ulcer Monitoring

    SBC: STOECKER MD, WILLIAM V            Topic: 600

    AbstractSmart Sensor Bandage for Ulcer Monitoring Non healing pressure ulcers result in approximately $billion in additional treatments each year in the United Statesraising in hospital mortality by nearly threefold and lengthening hospital stay by more than double when ulcers are presentThis burden is particularly pronounced in assisted living facilities where occurrence is high and skilled nursi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Develop novel lutein biomanufacturing in a nonmodel yeast via engineered metabolons and metabolic analyses

    SBC: Arch Innotek, LLC            Topic: 300

    Project Summary Arch Innotek proposes to develop a sustainablecost effective fermentation process to produce lutein using engineered yeastLutein is an important antioxidant compound that can slow the progression of vision loss caused by age related macular degenerationAMDcataractsand retinitis pigmentosaAside from protecting eyesdietary intake of lutein can reduce risk of skin disordersseveral typ ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. An unique patient population for clinical trials against noise-induced hearing loss

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: NIDCD

    AbstractNoise is the number one occupational and environmental hazardand noiseinduced hearing lossNIHLis one common form of sensorineural hearing deficitonly second to age related hearing lossCurrently no drug preventing NIHL is approved by the United States Food and Drug AdministrationFDAOne major challenge for the introduction of such interventions is the need to identify appropriate human popul ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Expansion of Immuno-CometChip Platform

    SBC: Amelia Technologies LLC            Topic: NIEHS

    Project SummaryThe objective of this supplementation request is to further our recent advances in the development of thewell Immuno CometChip assay results and build a prototypewell preformer giving the assay more utility and increasing commercial viability

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. ErythroMer: Nanoscale Bio-Synthetic Red Cell Substitute

    SBC: KaloCyte Inc            Topic: NHLBI

    PROJECT SUMMARY There is need for an artificial oxygenOcarrier to substitute for banked blood in settings wherestored blood is unavailablepre hospital care transportaustere environmentsundeveloped countriesorundesirabletransfusion risk exceeds benefitTo address this needwe developedErythroMerEMa first inclass nano cyte blood substituteEM is a deformablecross linked polymeric nanoparticle that inco ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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