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DESCRIPTION provided by applicant MicroRNAs miRNAs are involved in many diverse biological processes and a single miRNA can modulate the expression of hundreds of gene targets Changes in miRNA expression could have profound biological impacts leading to a variety of human diseases To date most miRNA expression profiling studies have relied on microarrays or high throughput RNA sequencing ...

DESCRIPTION provided by applicant RNA interference RNAi is a small RNA guided gene silencing process within living cells The RNAi technique is widely used in both biological research and clinical applications because it has the ability to knockdown essentially any gene of interest However one major unresolved issue in RNAi studies is non specific gene silencing It is well known that in ...

DESCRIPTION provided by applicant Clinical Importance Almost million dental implants were placed worldwide in with million of these procedures taking place in the United States The worldwide market for these implants is expected to increase to $ $ billion in revenue by as dental implant manufactures target and train general dentists non surgically trained to perform th ...

DESCRIPTION provided by applicant Antibiotic resistance complicates the majority of Staphylococcus aureus S aureus infections as a full two thirds of hospital associated S aureus infections and of those acquired in the community are now methicillin resistant MRSA MRSA causes andgt infections in the US each year and it is responsible for half of all deaths caused by drug re ...