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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Clinical Cytophone platform for detection of circulating melanoma cells.

    SBC: CytoAstra, LLC            Topic: NCI

    Most patients with melanoma die from metastatic disease as the result of circulating tumor cells (CTCs) spreading from a primary tumor through the blood to vital organs. Despite significant progress in the development of in vitro CTC-detection assays, they still have low sensitivity due to the small samples of blood taken. To overcome these problems, we developed in vivo photoacoustic (PA) flow cy ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Antioxidant enzyme-loaded Pro-NP for treatment of TBI.

    SBC: ProTransit Nanotherapy, LLC            Topic: 106

    ABSTRACT Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide and comes with a significant economic burden associated with emergency room visits and hospitalizations. Oxidative stress- mediated secondary injury post-TBI is a considerable risk factor for mortality and long-term impairment. Immediately following TBI, a cascade of biological responses leads to i ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. An Economical Point-of-Care Software Solution Prototype for Medication Prior Authorization

    SBC: Breezmed            Topic: 104

    ABSTRACT This STTR Phase I project uses mixed-method formative evaluation strategies to develop, test, and evaluate an alpha prototype of Breezmed, a point-of-care electronic prior authorization web-based platform. Prior authorization burdens the current medical system, hampering a provider’s ability to efficiently prescribe medication and in a timely fashion. This often leads to treatment non-c ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes

    SBC: CellGro Technologies, LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Multicolor Photoacoustic Malaria Detector

    SBC: CytoAstra, LLC            Topic: NIAID

    Summary Malaria continues to be a global health prioritywith almost half of the world s populationbillionat risk and arounddeaths each yearOvertreatment is caused by lack of diagnosis and contributes to resistancea huge threat as illustrated by artemisinin resistance in Southeast AsiaLittle progress has been made in the novel methods to diagnose malarialet alone in reliably identifying asymptomati ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Roboglasses electronic travel aid with hands free obstacle avoidance for blind and vision impaired users

    SBC: FAUXSEE INNOVATIONS LLC            Topic: N

    Project Summary Fauxsee Innovations LLC The objective of this project is to assess the efficacy and usability of an electronic travel aid ETA called Roboglasses developed through an NSF SBIR grant in reducing head and upper body injuries sustained by blind people who currently use a cane and or guide dog for mobility Canes and dogs only provide information about ground level obstructions ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Noninvasive Home Assessment of Cardiac Filling Pressure to Identify Heart Failure Patients at High Risk for Readmission

    SBC: Vixiar Medical, Inc            Topic: NHLBI

    Congestive heart failure CHF is the most common reason for hospitalization in the U S with over million admissions per year Patients admitted with CHF usually need IV diuretics to promote fluid removal The readmission rate is high over by days and by days post discharge This also presents an enormous economic burden hospitalizations account for a large percentage of the ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

    SBC: Bohemica Pharmaceuticals, LLC            Topic: 100

    DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Ultrasensitive SERS Nano-Sensors for Pancreatic Cancer Diagnosis and Prognosis

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 103

    ABSTRACT Pancreatic cancer PC is an extremely aggressive malignancy with one of the worst prognoses of all cancers with a median survival of less than one year and an overall year survival of andlt With marked resistance to chemo and radiotherapies surgery is the only curative option In patients with localized disease and no lymph node or extra pancreatic metastases complete surgical ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer

    SBC: ACTORIUS PHARMACEUTICALS, LLC            Topic: 100

    DESCRIPTION provided by applicant Breast cancer is the most common type of cancer in women between the ages of and and responsible for deaths annually If treated early five year survival rates for patients in the U S are between and but drop to once metastatic breast cancer has developed Thus there is a great need to develop more effective treatment strategies fo ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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