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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ICU-CARE: An interactive mobile app to enhance the efficiency of daily informal caregiving in the intensive care unit

    SBC: SILICON CURES LLC            Topic: NINR

    PROJECT SUMMARY Actively involving informal caregivers in direct patient care at the bedside in the intensive care unit (ICU) has the potential to improve patient, informal caregiver, and health care system outcomes. Practice guidelines call for the liberal inclusion of informal caregivers as active partners in ICU care, but there is a critical, unmet need to develop tools that effectively operati ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Assembly of Large Aperture Space Telescopes in Cislunar Space Using a Swarm of Autonomous Small Satellites

    SBC: TEN ONE AEROSPACE LLC            Topic: T10

    NASA and industry are expressing a growing interest in autonomous robotic in-space assembly and servicing of large aperture space telescopes in cislunar space and at Sun-Earth L2 (SEL2). The recently launched James Webb Space Telescope (JWST) will operate at SEL2 for about 5-10 years until fuel for station keeping and attitude maneuvers is depleted. At this point JWST will essentially become inope ...

    STTR Phase I 2022 National Aeronautics and Space Administration
  3. Development of (R,S')-MNF as a dual-targeted therapy for pancreatic cancer

    SBC: PAZ PHARMACEUTICALS LLC            Topic: NCI

    Summary Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the U.S. with a 5-year survival rate of andlt;9%. The poor prognosis is partially due to resistance to standard of care treatments including gemcitabine (Gem) and Gem+nab-paclitaxel (n-PTX). The transcription factors HIF-1α and c-MYC are at the center of the mechanisms producing Gem and n-PTX resistance ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Targeted Radiotherapeuitc for Pancreatic Ductal Adenocarcinoma

    SBC: ADDUCTNE LLC            Topic: 102

    In 2020 alone, pancreatic cancer is estimated to have resulted in 47,050 deaths in the U.S. making it the fourth leading cause of cancer-related death. Pancreatic ductal adenocarcinoma (PDAC) makes up greater than 90% of all pancreatic cancer diagnoses and has an overall five-year survival rate of just 10%. New therapeutic options are needed to improve the poor prognosis for patients with PDAC. Ex ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. Antioxidant enzyme-loaded Pro-NP for treatment of TBI.

    SBC: PROTRANSIT NANOTHERAPY LLC            Topic: 106

    ABSTRACT Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide and comes with a significant economic burden associated with emergency room visits and hospitalizations. Oxidative stress- mediated secondary injury post-TBI is a considerable risk factor for mortality and long-term impairment. Immediately following TBI, a cascade of biological responses leads to i ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. An Economical Point-of-Care Software Solution Prototype for Medication Prior Authorization

    SBC: Breezmed            Topic: 104

    ABSTRACT This STTR Phase I project uses mixed-method formative evaluation strategies to develop, test, and evaluate an alpha prototype of Breezmed, a point-of-care electronic prior authorization web-based platform. Prior authorization burdens the current medical system, hampering a provider’s ability to efficiently prescribe medication and in a timely fashion. This often leads to treatment non-c ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Planetary-Scale Surface Feature Detection and Mapping for Future Exploration Missions

    SBC: New Rights Group, Inc.            Topic: T4

    Accurate navigation is a crucial part of both robotic and crewed exploration of other worlds. For missions to the surfaces of Mars and the Moon, mission planners will require increasingly autonomous guidance systems that support fast, efficient, and agile surface route planning. These navigation systems will rely on access to accurate and regularly updated maps of surface landmarks. In a recent pi ...

    STTR Phase I 2019 National Aeronautics and Space Administration
  8. Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes

    SBC: CellGro Technologies, LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Targeted Therapy for Myasthenia Gravis

    SBC: ARC Biotechnology LLC            Topic: NINDS

    Myasthenia gravis is a severe neuromuscular disease primarily caused by complement activating autoantibodies directed towards the skeletal muscle acetylcholine receptor. Present treatments are ineffectiveand uniformly have adverse effects, which negatively impact quality of life. Despite being a rare disease, myasthenia gravis is a costly one with a hospitalization expense of half a billion dollar ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Ultrasonic Additive Manufacturing of a deep throttling methane injector.

    SBC: T.G.V. ROCKETS INC.            Topic: T9

    Design and manufacture of a Liquid fuel injector optimized for Ultrasonic Additive Manufacturing. UAM delivers aerospace parts today at 97% of bulk material property and foil laydown rates at speeds significantly better then powder or filament process. UAM has traditionally been applied to 2-D planar surfaces. We will extend UAM into complex geometries and constructs suitable for rocket engine inj ...

    STTR Phase I 2018 National Aeronautics and Space Administration
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