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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ICU-CARE: An interactive mobile app to enhance the efficiency of daily informal caregiving in the intensive care unit

    SBC: SILICON CURES LLC            Topic: NINR

    PROJECT SUMMARY Actively involving informal caregivers in direct patient care at the bedside in the intensive care unit (ICU) has the potential to improve patient, informal caregiver, and health care system outcomes. Practice guidelines call for the liberal inclusion of informal caregivers as active partners in ICU care, but there is a critical, unmet need to develop tools that effectively operati ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Towards intra-operative guidance in brain tumor surgery using real-time resting-state functional MRI

    SBC: NeurInsight, LLC            Topic: NINDS

    SummaryResting-state functional MRI (rsfMRI) is a rapidly developing task-free approach for presurgical mapping. It can complement task-based functional MRI (tfMRI) in patients who have difficulties performing tasks and efficiently map resting state networks (RSNs) in regions that are not typically mapped with tfMRI due to time constraints, such as frontal cortex. It has the potential to provide i ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. A Machine Learning Algorithm to Assess Functional "Brain Age" from an In-Home EEG Sleepband

    SBC: NEUROGENECES, INC.            Topic: NIA

    1 PROJECT SUMMARY2 Humans are living longer, resulting in our bodies outliving our brains. Although behavioral changes and better3 management of health conditions can help reverse or slow down premature decline in brain function, pre-4 symptomatic adults are not identified early enough when these changes would make the most significant positive5 impact. Effective intervention requires early detect ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States

    SBC: NEW MEXICO START-UP FACTORY II LLC            Topic: NIGMS

    Project Summary As a participant in the new IDeA Regional Entrepreneurship Development (I-RED) program, the goal of this proposal is to create an educational product to promote entrepreneurism and commercialization in the Mountain West region of IDeA states. The educational product and overall program are intended to address the needs of IDeA state academic institutions in developing and strengthe ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Development of (R,S')-MNF as a dual-targeted therapy for pancreatic cancer

    SBC: PAZ PHARMACEUTICALS LLC            Topic: NCI

    Summary Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the U.S. with a 5-year survival rate of andlt;9%. The poor prognosis is partially due to resistance to standard of care treatments including gemcitabine (Gem) and Gem+nab-paclitaxel (n-PTX). The transcription factors HIF-1α and c-MYC are at the center of the mechanisms producing Gem and n-PTX resistance ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. A Broadband and Compact Dual Comb Spectrometer for Precise Field Detection of Trace Elements and Chemicals

    SBC: OPTICSLAH, LLC            Topic: DTRA20B003

    There is a growing need to accurately characterize nuclear materials not only for nuclear safeguards and nonproliferation treaty verification but also for forensics and provenance. Presently, nuclear material identification requires samples to be collected and sent to laboratories for analysis using large and expensive equipment, such as inductively coupled plasma mass spectrometers (ICP-MS) or se ...

    STTR Phase I 2021 Department of DefenseDefense Threat Reduction Agency
  7. Development of a Targeted Radiotherapeuitc for Pancreatic Ductal Adenocarcinoma

    SBC: ADDUCTNE LLC            Topic: 102

    In 2020 alone, pancreatic cancer is estimated to have resulted in 47,050 deaths in the U.S. making it the fourth leading cause of cancer-related death. Pancreatic ductal adenocarcinoma (PDAC) makes up greater than 90% of all pancreatic cancer diagnoses and has an overall five-year survival rate of just 10%. New therapeutic options are needed to improve the poor prognosis for patients with PDAC. Ex ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Rifampin potentiation in NTM

    SBC: SpinCeutica, Inc.            Topic: NIAID

    Non-tuberculous mycobacterial lung disease (NTM-LD) caused by Mycobacterium avium complex is a serious chronic infection causing permanent lung damage, and is difficult to treat, typically requiring 12-24 months of treatment with rifampin, macrolide and ethambutol. We hypothesize that combined deuterated ambroxol and [acyl-13C]INH will allow both pharmacokinetic and pharmacodynamic enhancement of ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an innovative diabetes therapeutic via GPER targeting

    SBC: GPER G-1 Development Group LLC            Topic: 400

    PROJECT SUMMARY Diabetes mellitus is a group of metabolic disorders characterized by high blood sugar, which is caused by deficiencies in insulin secretion and/or insulin action. Chronic diabetes can result in complications such as heart and peripheral vascular disease, kidney failure, limb amputation, and blindness and can even contribute to carcinogenesis. Diabetes represents a significant healt ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Antioxidant enzyme-loaded Pro-NP for treatment of TBI.

    SBC: PROTRANSIT NANOTHERAPY LLC            Topic: 106

    ABSTRACT Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide and comes with a significant economic burden associated with emergency room visits and hospitalizations. Oxidative stress- mediated secondary injury post-TBI is a considerable risk factor for mortality and long-term impairment. Immediately following TBI, a cascade of biological responses leads to i ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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