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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. MR Virtual Pathology of the Prostate

    SBC: QMIS            Topic: 102

    QMIS, LLC (Quantitative MRI Solutions) is developing a new MRI-based tool that reliably screens for prostate cancer (PCa). PCa is a leading cause of death (29,500 U.S. deaths in 2018). Current methods (PSA and digital rectal exam) are unreliable; they result in unnecessary biopsies while missing clinically significant PCa. MRI has potential to detect PCa at an early stage when it is highly curable ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Optimization of Cannabinoids for Development as FDA-Approved Migraine Therapeutics

    SBC: Schedule 1 Therapeutics, Inc.            Topic: NIDA

    Optimization of Cannabinoids for Development as FDA-Approved Migraine Therapeutics Project Summary: Migraine is a disorder that affects 15% of all people in the US, the majority of which are women. Migraine is one of the leading causes of missed days at work during which patients are unable to complete many daily activities. Currently approved treatments for migraine are not satisfying with at mos ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Antioxidant enzyme-loaded Pro-NP for treatment of TBI.

    SBC: ProTransit Nanotherapy, LLC            Topic: 106

    ABSTRACT Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide and comes with a significant economic burden associated with emergency room visits and hospitalizations. Oxidative stress- mediated secondary injury post-TBI is a considerable risk factor for mortality and long-term impairment. Immediately following TBI, a cascade of biological responses leads to i ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. An Economical Point-of-Care Software Solution Prototype for Medication Prior Authorization

    SBC: Breezmed            Topic: 104

    ABSTRACT This STTR Phase I project uses mixed-method formative evaluation strategies to develop, test, and evaluate an alpha prototype of Breezmed, a point-of-care electronic prior authorization web-based platform. Prior authorization burdens the current medical system, hampering a provider’s ability to efficiently prescribe medication and in a timely fashion. This often leads to treatment non-c ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Step UP for STEM and Health Careers: An Intervention to Reduce STEM related biases towards young women and minorities

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: NICHD

    Project Abstract The National Institutes of Health has a stated commitment to diversifying the national scientific workforce. While diversity has many dimensions, women and underrepresented minorities (i.e., black, Latinx, indigenous, and Pacific Islanders) are particularly underrepresented in Science, Technology, Engineering, and Mathematics (STEM) and health careers. Rather than ability, dispari ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Correlative nonvital standard histopathology and vital multiphoton prehistopathology

    SBC: LiveBx, LLC            Topic: 400

    SUMMARY A common practice in medicine for handling freshly biopsied human tissue is to rapidly put it into a formalin solution. This “fixation” preserves the tissue from decay, allowing transportation to a (remote) pathology laboratory for standard histopathology or other biochemical/genetical analyses. However, formalin instantly “kills” the tissue, so that the biochemical and metabolic f ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel DHA Treatment Approach for Alzheimer's Disease

    SBC: Orochem Technologies Inc.            Topic: NIA

    Alzheimer’s disease (AD) and related dementia (ADRD) are adversely impacting the healthy lifespan in our aging population. Fish oil has been suggested to improve AD/ADRD outcomes. The omega 3 fatty acids (Om3FA) in fish oil in particular DHA (docosahexaenoic acid) is a key molecule. Some data exists that DHA is beneficial for protection against age related cognitive decline and related dementia ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Prevention of GVHD by a probiotic exopolysaccharide.

    SBC: HASENTECH            Topic: NIAID

    Abstract Graft versus host disease (GVHD) is an often lethal complication from allogeneic hematopoietic stem cell transplantation used as treatment for a variety of hematologic malignancies. GVHD results from an attack on host cells by alloreactive T cells of the donor. Standard prevention and treatment for GVHD is administration of broadly immunosuppressive drugs, which suppress alloreactive T ce ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Development of digital and interactive methods to teach immunology

    SBC: FLUID CONTENT INC            Topic: NIGMS

    Abstract The goal of this project is to develop a digital media based program to teach high school student about immunologyWe will develop an interactive digital media to teach minority studentshigh schoolon the introduction of immunology and compare the efficacy of learning between traditional teaching and interactive mediaWe will develop three curriculums to teach group of high school students r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development of group 2 influenza A virus entry inhibitors

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the Orthomyxoviridae family with a negative-sense, segmented RNA genome, which can cause seasonal or pandemic flu with high morbidity and significant mortality. Vaccination is the most prevalent prophylactic means for controlling influenza infections. However, an effective vaccine usually takes at least 6 months to develop for the circulating strains. Furthermore, vac ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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