Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Development of digital and interactive methods to teach immunology

    SBC: FLUID CONTENT INC            Topic: NIGMS

    Abstract The goal of this project is to develop a digital media based program to teach high school student about immunologyWe will develop an interactive digital media to teach minority studentshigh schoolon the introduction of immunology and compare the efficacy of learning between traditional teaching and interactive mediaWe will develop three curriculums to teach group of high school students r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of group 2 influenza A virus entry inhibitors

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the Orthomyxoviridae family with a negative sensesegmented RNA genomewhich can cause seasonal or pandemic flu with high morbidity and significant mortalityVaccination is the most prevalent prophylactic means for controlling influenza infectionsHoweveran effective vaccine usually takes at leastmonths to develop for the circulating strainsFurthermorevaccination has limi ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes

    SBC: CellGro Technologies, LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Multi-Modal Wearable Sensing for the Prediction of Pre-Term Labor

    SBC: Sonica LLC            Topic: NICHD

    Preterm birthPTBdelivery prior toweeks gestational ageaccounts forof all births and remains the leading cause of neonatal deathThe majority of PTB is preceded by spontaneous preterm laborPTLCurrentlythere is a major unmet need for methods to identify women at risk of PTL and provide an early warning system for potential interventionhome uterine monitoringHUMis one approach that has shown some prom ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Developing Insulin-like growth factor binding protein 2(IGFBP2)peptide fragment-based therapeutics to treat functional and behavioral deficits in Phelan-McDermid Syndrome.

    SBC: ALISBIO LLC            Topic: 101

    ABSTRACTAlisBio is developing novel therapeutics based on Insulin like growth factor binding proteinIGFBPpeptide fragments to treat functional and behavioral deficits in Phelan McDermid SyndromePMSa monogenic form of autism spectrum disorderASDaccounting forof ASD diagnosesThe focus of this Phase I grant is to demonstrate that proprietary IGFBPmimetic peptide fragments reverse disease relevant cel ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Array Based Affinity Selection

    SBC: Tango Biosciences Inc.            Topic: 300

    Project SummaryAffinity reagents are useful tools for detectingmonitoringand quantifying individual proteins in complex mixturesModern recombinant biology and protein engineering techniques generate highaffinityhigh specificity reagents that overcome some of the limitations of polyclonal and monoclonal antibodiesHoweverlimited availability of target proteini eantigenprevents the selection of recom ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Improving the Pelvic Health of Women and Girls Through the Use of a Digital Coaching Platform

    SBC: Below Your Belt L3C            Topic: NICHD

    ABSTRACT More thanmillion women suffer from pelvic health disordersPHDsin the United Statesa number that is projected to nearly double byThese conditions cost the healthcare system billions annually and negatively affect educational and employment opportunitiesquality of lifeand fertility of patientsWhile studies suggest that PHDs can be managed and improved with educationpractitioners are often c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Beyond the pump: a novel shape memory alloy penile prosthesis

    SBC: Uronext LLC            Topic: 400

    Abstract Erectile dysfunctionEDis a multifactorial disease that affects approximatelymillion American men and is continuing to increase with the increasing prevalence of diabeteshypertension and cardiovascular diseaseWhen first line and second line medications such as the phosphodiesteraseinhibitorPDE iclass of medications or direct injections failsurgical implantation of penile prostheses offers ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Implantable Microarray Probe for Real-Time Glutamate and GABA Detection

    SBC: Alcorix Co.            Topic: 999

    Project SummaryThere is an enormous need for the development of a new class of neurotransmitterNTsensors that are versatileselectivesensitive and reliable to allow investigation of the neurobiological mechanisms of behavior and disease symptomsThis STTR proposal will focus on implementing a novel microarray probe for in vivoreal time sensing of glutamateGLUand gamma aminobutyric acidGABAGLU and GA ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A digital brain-gut therapy platform for enhanced management of Irritable Bowel Syndrome

    SBC: METAME HEALTH,INC            Topic: R

    Project Summary Abstract Irritable Bowel Syndrome IBS is a chronic and costly digestive condition characterized by abdominal pain and altered bowel habits diarrhea constipation or mixed type IBS is a disorder of brain gut dysregulation including the amplification of normal gut signals at the level of the brain Yet most medical therapies for IBS to date have focused on symptom management and dietar ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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